methyl (R)-3-(1H-naphtho[1,8-de][1,3,2]-diazaborinin-2(3H)-yl)-3-phenylpropanoate

Base Information

Chemical Name:methyl (R)-3-(1H-naphtho[1,8-de][1,3,2]-diazaborinin-2(3H)-yl)-3-phenylpropanoate
CAS No.:1393880-59-5
Molecular Formula:C₂₀H₁₉BN₂O₂
Molecular Weight:330.194
Hs Code.:

Synonyms:methyl (R)-3-(1H-naphtho[1,8-de][1,3,2]-diazaborinin-2(3H)-yl)-3-phenylpropanoate

Suppliers and Price of methyl (R)-3-(1H-naphtho[1,8-de][1,3,2]-diazaborinin-2(3H)-yl)-3-phenylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (R)-3-(1H-naphtho[1,8-de][1,3,2]-diazaborinin-2(3H)-yl)-3-phenylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (R)-3-(1H-naphtho[1,8-de][1,3,2]-diazaborinin-2(3H)-yl)-3-phenylpropanoate

There total 10 articles about methyl (R)-3-(1H-naphtho[1,8-de][1,3,2]-diazaborinin-2(3H)-yl)-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: CH₃OCOCHCHB(NHC₁₀H₆NH)

: 100-58-3
phenylmagnesium bromide

: 1393880-59-5
methyl (R)-3-(1H-naphtho[1,8-de][1,3,2]-diazaborinin-2(3H)-yl)-3-phenylpropanoate

Guidance literature:: With CuI; (R)-(C₁₀H₆P(C₆H₄CH₃)2)2; In CH₂Cl₂; react. boron compd. with Mg compd. (2.5 equivs.) in CH2Cl2 at -78°C for 2.0 h in the presence of CuI and (R)-Tol-BINAP; analyzed by chiral HPLC; ee 89%;

Reference yield:

: 1224722-38-6
trans-methyl 3-(1H-naphtho[1,8-de][1,3,2]diazoborinin-2(3H)-yl)-acrylate

: 100-58-3
phenylmagnesium bromide

: 1393880-59-5
methyl (R)-3-(1H-naphtho[1,8-de][1,3,2]-diazaborinin-2(3H)-yl)-3-phenylpropanoate

: 1393880-59-5
(S)-methyl 3-(1H-naphtho[1,8-de][1,3,2]diazaborinin-2(3H)-yl)-3-phenylpropanoate

Guidance literature:: trans-methyl 3-(1H-naphtho[1,8-de][1,3,2]diazoborinin-2(3H)-yl)-acrylate; With copper(l) iodide; (R)-tol-BINAP; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

phenylmagnesium bromide; In dichloromethane; at -78 ℃; for 2.03333h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

Reference yield:

: 1224722-38-6
trans-methyl 3-(1H-naphtho[1,8-de][1,3,2]diazoborinin-2(3H)-yl)-acrylate

: 100-58-3
phenylmagnesium bromide

: 1393880-59-5
methyl (R)-3-(1H-naphtho[1,8-de][1,3,2]-diazaborinin-2(3H)-yl)-3-phenylpropanoate

: 1393880-59-5
(S)-methyl 3-(1H-naphtho[1,8-de][1,3,2]diazaborinin-2(3H)-yl)-3-phenylpropanoate

Guidance literature:: trans-methyl 3-(1H-naphtho[1,8-de][1,3,2]diazoborinin-2(3H)-yl)-acrylate; With copper(l) iodide; (R)-tol-BINAP; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

phenylmagnesium bromide; In dichloromethane; at -78 ℃; for 2.03333h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;