(1E,5E)-1,6-diphenyl-1,5-hexadiene

Base Information

• Chemical Name: (1E,5E)-1,6-diphenyl-1,5-hexadiene
• CAS No.: 58463-02-8
• Molecular Formula: C₁₈H₁₈
• Molecular Weight: 234.341
• Mol file: 58463-02-8.mol

Synonyms:(1E,5E)-1,6-diphenyl-1,5-hexadiene

Chemical Property of (1E,5E)-1,6-diphenyl-1,5-hexadiene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1E,5E)-1,6-diphenyl-1,5-hexadiene

There total 83 articles about (1E,5E)-1,6-diphenyl-1,5-hexadiene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

Cinnamyl acetate (21040-45-9) → (1E,5E)-1,6-diphenyl-1,5-hexadiene (58463-02-8)

Guidance literature:

With manganese; (1,2-dimethoxyethane)dichloronickel(II); 4,4',4-tri-tert-butyl-2,2':6',2-terpyridine; In N,N-dimethyl-formamide; at 40 ℃; for 24.5h;

DOI:10.1039/c0cc01716g

Reference yield: 86.0%

(2E)-3-phenyl-2-propen-1-ol (4407-36-7) + 2-cinnamyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → (1E,5E)-1,6-diphenyl-1,5-hexadiene (58463-02-8)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; triphenylphosphine; In acetonitrile; at 50 ℃; for 12h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.0c01424

Reference yield: 86.0%

trans-3-phenylprop-2-enyl chloride (21087-29-6) → (1E,5E)-1,6-diphenyl-1,5-hexadiene (58463-02-8)

Guidance literature:

With carbon monoxide; potassium carbonate; triphenylphosphine; palladium diacetate; titanium nitride; In N,N,N,N,N,N-hexamethylphosphoric triamide; toluene; at 20 ℃;

DOI:10.1016/j.tetlet.2004.02.072

upstream raw materials:

phosgene

trans-3-phenylprop-2-enyl chloride

diethyl ether

methylmagnesium bromide

Downstream raw materials:

1,6-diphenyl-hexa-1,3,5-triene

(2S,5S)-2,5-dibenzylpyrrolidine

(2R,5R)-1,6-diphenylhexane-2,5-diol

(4R,7R)-4,7-Dibenzyl-[1,3,2]dioxathiepane 2,2-dioxide