1-(4-aminosulfonylphenyl)-3-trifluoromethyl-5-(3-acetoxyphenyl)pyrazole

Base Information

Chemical Name:1-(4-aminosulfonylphenyl)-3-trifluoromethyl-5-(3-acetoxyphenyl)pyrazole
CAS No.:1338216-13-9
Molecular Formula:C₁₈H₁₄F₃N₃O₄S
Molecular Weight:425.388
Hs Code.:

Synonyms:1-(4-aminosulfonylphenyl)-3-trifluoromethyl-5-(3-acetoxyphenyl)pyrazole

Suppliers and Price of 1-(4-aminosulfonylphenyl)-3-trifluoromethyl-5-(3-acetoxyphenyl)pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 1-(4-aminosulfonylphenyl)-3-trifluoromethyl-5-(3-acetoxyphenyl)pyrazole

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of 1-(4-aminosulfonylphenyl)-3-trifluoromethyl-5-(3-acetoxyphenyl)pyrazole

There total 4 articles about 1-(4-aminosulfonylphenyl)-3-trifluoromethyl-5-(3-acetoxyphenyl)pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 1335246-17-7
4-(5-(3-hydroxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide

: 75-36-5
acetyl chloride

: 1338216-13-9
1-(4-aminosulfonylphenyl)-3-trifluoromethyl-5-(3-acetoxyphenyl)pyrazole

Guidance literature:: With triethylamine; In diethyl ether; at 0 - 25 ℃;
DOI:10.1016/j.bmcl.2011.08.053

Reference yield:

: 4-[5-(3-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide

: 1338216-13-9
1-(4-aminosulfonylphenyl)-3-trifluoromethyl-5-(3-acetoxyphenyl)pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium thioethylate / N,N-dimethyl-formamide / 3 h / 120 °C

2: triethylamine / diethyl ether / 0 - 25 °C

With triethylamine; sodium thioethylate; In diethyl ether; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2011.08.053

Reference yield:

: 433244-74-7
C₁₁H₉F₃O₃

: 1338216-13-9
1-(4-aminosulfonylphenyl)-3-trifluoromethyl-5-(3-acetoxyphenyl)pyrazole

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 24 h / Reflux

2: sodium thioethylate / N,N-dimethyl-formamide / 3 h / 120 °C

3: triethylamine / diethyl ether / 0 - 25 °C

With triethylamine; sodium thioethylate; In diethyl ether; ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2011.08.053