Technology Process of 13-cyano-9,12-di(phenylmethyl)-2,2-dimethyl-3-oxa-4-oxo-5,9,12-triazotridecane
There total 10 articles about 13-cyano-9,12-di(phenylmethyl)-2,2-dimethyl-3-oxa-4-oxo-5,9,12-triazotridecane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium fluoride; Celite;
In
acetonitrile;
at 85 ℃;
for 12h;
DOI:10.1002/jhet.5570300532
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 81 percent / tetrahydrofuran / 6 h / Ambient temperature
2: 87 percent / potassium fluoride/celite / acetonitrile / 12 h / 85 °C
3: 92 percent / H2, aq. NaOH / Raney Ni / ethanol / 12 h / 2327.2 Torr
4: magnesium sulfate / methanol / 4 h / Ambient temperature
5: NaBH4 / methanol / Ambient temperature
6: 96 percent / KF/celite / acetonitrile / 12 h / 85 °C
With
potassium fluoride; sodium hydroxide; sodium tetrahydroborate; Celite; hydrogen; magnesium sulfate;
nickel;
In
tetrahydrofuran; methanol; ethanol; acetonitrile;
DOI:10.1002/jhet.5570300532
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 87 percent / potassium fluoride/celite / acetonitrile / 12 h / 85 °C
2: 92 percent / H2, aq. NaOH / Raney Ni / ethanol / 12 h / 2327.2 Torr
3: magnesium sulfate / methanol / 4 h / Ambient temperature
4: NaBH4 / methanol / Ambient temperature
5: 96 percent / KF/celite / acetonitrile / 12 h / 85 °C
With
potassium fluoride; sodium hydroxide; sodium tetrahydroborate; Celite; hydrogen; magnesium sulfate;
nickel;
In
methanol; ethanol; acetonitrile;
DOI:10.1002/jhet.5570300532
