Methyl 3,5-Dichloro-2-hydroxy-4-methoxy-6-propylbenzoate

Base Information

• Chemical Name: Methyl 3,5-Dichloro-2-hydroxy-4-methoxy-6-propylbenzoate
• CAS No.: 121869-60-1
• Molecular Formula: C₁₂H₁₄Cl₂O₄
• Molecular Weight: 293.147
• Mol file: 121869-60-1.mol

Synonyms:Methyl 3,5-Dichloro-2-hydroxy-4-methoxy-6-propylbenzoate

Chemical Property of Methyl 3,5-Dichloro-2-hydroxy-4-methoxy-6-propylbenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of Methyl 3,5-Dichloro-2-hydroxy-4-methoxy-6-propylbenzoate

There total 10 articles about Methyl 3,5-Dichloro-2-hydroxy-4-methoxy-6-propylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-Chloro-6-hydroxy-4-methoxy-2-propyl-benzoic acid methyl ester (192212-02-5) → Methyl 3,5-Dichloro-2-hydroxy-4-methoxy-6-propylbenzoate (121869-60-1)

Guidance literature:

With sulfuryl dichloride; for 3h; Ambient temperature;

DOI:10.1016/S0040-4039(97)01000-9

Reference yield: 61.0%

methyl 2-hydroxy-4-methoxy-6-(n-propyl)benzoate (57074-20-1) → Methyl 3,5-Dichloro-2-hydroxy-4-methoxy-6-propylbenzoate (121869-60-1)

Guidance literature:

With sulfuryl dichloride; for 0.166667h; Ambient temperature;

Reference yield:

2,4-dihydroxy-6-n-propylbenzoic acid, methyl ester (55382-52-0) → Methyl 3,5-Dichloro-2-hydroxy-4-methoxy-6-propylbenzoate (121869-60-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent Turnov_. / K₂CO₃ / acetone / 5 h

2: 61 percent / sulfuryl chloride / 0.17 h / Ambient temperature

With sulfuryl dichloride; potassium carbonate; In acetone;

upstream raw materials:

methyl 2-hydroxy-4-methoxy-6-(n-propyl)benzoate

3-Chloro-6-hydroxy-4-methoxy-2-propyl-benzoic acid methyl ester

1,3-dimethoxy-5-propylbenzene

3,5-dimethoxybenzaldehdye

Downstream raw materials:

Differanisole A