55382-52-0

Usage

Chemical Properties

Pale yellow solid.

Uses

Methyl Divarinolcarboxylate is used in methods of manufacturing Cannabidiol or Cannabidivarin.

Upstream product

• 102342-54-1 1,3,5-tris(trimethylsiloxy)-1-methoxyhexa-1,3,5-triene 
• 141-75-3 butyryl chloride 
• 491-62-3 divaricatic acid 
• 5609-09-6 trans 3-hepten-2-one 
• 108-59-8 malonic acid dimethyl ester 
• 89-86-1 4-hydroxysalicylic acid 
• 67-56-1 methanol 
• 4707-50-0 2,4-dihydroxy-6-propylbenzoic acid 
• 491-57-6 2-hydroxy-4-(2-hydroxy-4-methoxy-6-pentyl-benzoyloxy)-6-propyl-benzoic acid 
• 43083-12-1 1,1,1-trimethoxybutane 
• 674-82-8 4-methyleneoxetan-2-one 
• 30414-54-1 methyl 3-oxohexanoate 
• 186581-53-3 diazomethane 

Downstream Products

• 24274-48-4 cannabidivarin 
• 31262-37-0 tetrahydrocannabivarin 
• 64898-07-3 CBDVA-Methylester 
• 64898-09-5 5-hydroxy-2-methyl-2-(4-methyl-pent-3-enyl)-7-propyl-2H-chromene-6-carboxylic acid methyl ester 
• 94474-29-0 Differanisole A 
• 121869-60-1 Methyl 3,5-Dichloro-2-hydroxy-4-methoxy-6-propylbenzoate 
• 6245-56-3 2-hydroxy-4-methoxy-6-propylbenzoic acid 
• 110828-01-8 methyl 4-hydroxy-2-methoxy-6-propylbenzoate 
• 55382-55-3 4-Benzyloxy-2-methoxy-6-propyl-benzoic acid methyl ester 
• 55382-54-2 methyl 4-benzyloxy-2-hydroxy-6-propylbenzoate 
• 57074-20-1 methyl 2-hydroxy-4-methoxy-6-(n-propyl)benzoate 
• 64898-02-8 cannabichromevarinic acid 

Relevant academic research and scientific papers

SYNTHESIS OF PHYTOCANNABINOIDS INCLUDING A DECARBOXYLATION STEP

method for decarboxylating a carboxylated phytocannabinoid compound of Formula I to form a phytocannabinoid compound of Formula II: Formula I Formula II wherein: R1 is selected from the group consisting of: substituted or unsubstituted C1-C5 alkyl; R2 is selected from the group consisting of: OH or O, and R3 is selected from the group consisting of: a substituted or unsubstituted cyclohexene, a substituted or unsubstituted C2-C8 alkene, or a substituted or unsubstituted C2-C8 dialkene; or R2 is O, and R2 and R3 together form a ring structure in which R2 is an internal ring atom; wherein the method includes heating a reaction mixture comprising the carboxylated phytocannabinoid compound and a polar aprotic solvent in the presence of a LiCl for a time sufficient to decarboxylate at least a portion of the carboxylated phytocannabinoid compounds and form the phytocannabinoid compound.

SYNTHESIS OF PHYTOCANNABINOIDS INCLUDING A DEMETHYLATION STEP

A method for demethylating a methylated phytocannabinoid compound of Formula I to form a phytocannabinoid compound of Formula II: Formula I Formula II wherein: R1 is selected from the group consisting of: substituted or unsubstituted C1-C5 alkyl; R2 is selected from the group consisting of: OH or O, and R3 is selected from the group consisting of: a substituted or unsubstituted cyclohexene, a substituted or unsubstituted C2-C8 alkene, or a substituted or unsubstituted C2-C8 dialkene; or R2 is O, and R2 and R3 together form a ring structure in which R2 is an internal ring atom; wherein the method includes: heating a reaction mixture comprising the methylated phytocannabinoid compounds and a polar aprotic solvent in the presence of a dissolved inorganic alkaline salt for a time sufficient to demethylate at least a portion of the methylated phytocannabinoid compounds and form the phytocannabinoid compound.

BIOENZYMATIC SYNTHESIS OF THC-v, CBV AND CBN AND THEIR USE AS THERAPEUTIC AGENTS

The present invention provides methods for producing cannabinoids. More specifically, the invention is directed to the bio-enzymatic synthesis of THC-v, CBV and CBN by contacting a compound according to Formula I with a cannabinoid synthase enzyme. Also described is a system for producing these pharmaceutically important cannabinoids and the use of such cannabinoids as therapeutic agents.

Synthetic Microbial Chemistry, XXI. Synthesis of Differanisole A, an Inducer of Differentiation

The synthesis of differanisole A (3,5-dichloro-2-hydroxy-4-methoxy-6-propylbenzoic acid, 1) was achieved in five steps from 2-pentanone.

Naturally Occurring Dibenzofurans. VIII The Synthesis of Isodidymic acid

The synthesis of the lichen dibenzofuran isodidymic acid (2) (3-hydroxy-7-methoxy-9-pentyl-1-propyldibenzofuran-2-carboxylic acid) by intramolecular Ullmann coupling of methyl 3-iodo-4-(2'-iodo-5'-methoxy-3'-pentylphenoxy)-6-methoxy-2-propylbenzoate (22), and further transformations, is described.

Chemistry of 1,3,5-Tris(trimethylsiloxy)-1-methoxyhexa-1,3,5-triene, a β-Tricarbonyl Trianion Equivalent

The title compound has been synthesized and its chemistry studied.Condensation with orthoesters, acid chlorides, or imidazolides gave aromatic compounds in a 5C + 1C condensation.A formal synthesis of lasiodiplodin has been completed.