55382-52-0

Basic information

• Product Name: 2,4-dihydroxy-6-propyl-benzoic acid methyl ester
• Synonyms: 2,4-dihydroxy-6-propyl-benzoic acid methyl ester;methyl 2,4-dihydroxy-6-propylbenzoate;2,4-dihydroxy-6-n-propylbenzoic acid, methyl ester
• CAS NO: 55382-52-0
• Molecular Formula: C₁₁H₁₄O₄
• Molecular Weight: 210.22646
• EINECS: -0
• Mol File: 55382-52-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 388.6±27.0 °C(Predicted)
• Appearance: /
• Density: 1.211±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 8.27±0.23(Predicted)
• CAS DataBase Reference: 2,4-dihydroxy-6-propyl-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dihydroxy-6-propyl-benzoic acid methyl ester(55382-52-0)
• EPA Substance Registry System: 2,4-dihydroxy-6-propyl-benzoic acid methyl ester(55382-52-0)

Safety Data

• Hazardous Substances Data: 55382-52-0(Hazardous Substances Data)

Usage

Description

2,4-dihydroxy-6-propyl-benzoic acid methyl ester is a carboxylate derivative and can be used as a pharmaceutical intermediate.

Chemical Properties

Pale yellow solid.

Uses

Methyl Divarinolcarboxylate is used in methods of manufacturing Cannabidiol or Cannabidivarin.

Upstream product

• 186581-53-3 diazomethane 
• 4707-50-0 2,4-dihydroxy-6-propylbenzoic acid 
• 5609-09-6 trans 3-hepten-2-one 
• 108-59-8 malonic acid dimethyl ester 
• 89-86-1 4-hydroxysalicylic acid 
• 67-56-1 methanol 
• 491-62-3 divaricatic acid 
• 491-57-6 2-hydroxy-4-(2-hydroxy-4-methoxy-6-pentyl-benzoyloxy)-6-propyl-benzoic acid 
• 102342-54-1 1,3,5-tris(trimethylsiloxy)-1-methoxyhexa-1,3,5-triene 
• 141-75-3 butyryl chloride 
• 43083-12-1 1,1,1-trimethoxybutane 
• 674-82-8 4-methyleneoxetan-2-one 
• 30414-54-1 methyl 3-oxohexanoate 

Downstream Products

• 64898-07-3 CBDVA-Methylester 
• 64898-09-5 5-hydroxy-2-methyl-2-(4-methyl-pent-3-enyl)-7-propyl-2H-chromene-6-carboxylic acid methyl ester 
• 31262-37-0 tetrahydrocannabivarin 
• 24274-48-4 cannabidivarin 
• 94474-29-0 Differanisole A 
• 121869-60-1 Methyl 3,5-Dichloro-2-hydroxy-4-methoxy-6-propylbenzoate 
• 6245-56-3 2-hydroxy-4-methoxy-6-propylbenzoic acid 
• 110828-01-8 methyl 4-hydroxy-2-methoxy-6-propylbenzoate 
• 55382-55-3 4-Benzyloxy-2-methoxy-6-propyl-benzoic acid methyl ester 
• 64898-02-8 cannabichromevarinic acid 
• 55382-54-2 methyl 4-benzyloxy-2-hydroxy-6-propylbenzoate 
• 57074-20-1 methyl 2-hydroxy-4-methoxy-6-(n-propyl)benzoate 

Relevant articles and documents

SYNTHESIS OF PHYTOCANNABINOIDS INCLUDING A DECARBOXYLATION STEP

method for decarboxylating a carboxylated phytocannabinoid compound of Formula I to form a phytocannabinoid compound of Formula II: Formula I Formula II wherein: R1 is selected from the group consisting of: substituted or unsubstituted C1-C5 alkyl; R2 is selected from the group consisting of: OH or O, and R3 is selected from the group consisting of: a substituted or unsubstituted cyclohexene, a substituted or unsubstituted C2-C8 alkene, or a substituted or unsubstituted C2-C8 dialkene; or R2 is O, and R2 and R3 together form a ring structure in which R2 is an internal ring atom; wherein the method includes heating a reaction mixture comprising the carboxylated phytocannabinoid compound and a polar aprotic solvent in the presence of a LiCl for a time sufficient to decarboxylate at least a portion of the carboxylated phytocannabinoid compounds and form the phytocannabinoid compound.

BIOENZYMATIC SYNTHESIS OF THC-v, CBV AND CBN AND THEIR USE AS THERAPEUTIC AGENTS

The present invention provides methods for producing cannabinoids. More specifically, the invention is directed to the bio-enzymatic synthesis of THC-v, CBV and CBN by contacting a compound according to Formula I with a cannabinoid synthase enzyme. Also described is a system for producing these pharmaceutically important cannabinoids and the use of such cannabinoids as therapeutic agents.

Chemistry of 1,3,5-Tris(trimethylsiloxy)-1-methoxyhexa-1,3,5-triene, a β-Tricarbonyl Trianion Equivalent

The title compound has been synthesized and its chemistry studied.Condensation with orthoesters, acid chlorides, or imidazolides gave aromatic compounds in a 5C + 1C condensation.A formal synthesis of lasiodiplodin has been completed.