tert-butyl {[5-bromo-4-(2-fluorophenyl)-1,3-thiazol-2-yl]methyl}methylcarbamate

Base Information

Chemical Name:tert-butyl {[5-bromo-4-(2-fluorophenyl)-1,3-thiazol-2-yl]methyl}methylcarbamate
CAS No.:1138033-68-7
Molecular Formula:C₁₆H₁₈BrFN₂O₂S
Molecular Weight:401.3
Hs Code.:

Synonyms:tert-butyl {[5-bromo-4-(2-fluorophenyl)-1,3-thiazol-2-yl]methyl}methylcarbamate

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Chemical Property of tert-butyl {[5-bromo-4-(2-fluorophenyl)-1,3-thiazol-2-yl]methyl}methylcarbamate

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Technology Process of tert-butyl {[5-bromo-4-(2-fluorophenyl)-1,3-thiazol-2-yl]methyl}methylcarbamate

There total 1 articles about tert-butyl {[5-bromo-4-(2-fluorophenyl)-1,3-thiazol-2-yl]methyl}methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1138033-64-3
tert-butyl {[4-(2-fluorophenyl)-1,3-thiazol-2-yl]methyl}methylcarbamate

: 1138033-68-7
tert-butyl {[5-bromo-4-(2-fluorophenyl)-1,3-thiazol-2-yl]methyl}methylcarbamate

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 3h;

Reference yield: 92.0%

: 50448-95-8
2-ethylhexyl 3-sulfanylpropanoate

: 1138033-68-7
tert-butyl {[5-bromo-4-(2-fluorophenyl)-1,3-thiazol-2-yl]methyl}methylcarbamate

: 1138035-43-4
2-ethylhexyl 3-{[2-{[(tert-butoxycarbonyl)(methyl)amino]methyl}-4-(2-fluorophenyl)-1,3-thiazol-5-yl]thio}propanoate

Guidance literature:: With caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In toluene; at 105 ℃; for 12h;

Reference yield: 91.0%

: 1138033-68-7
tert-butyl {[5-bromo-4-(2-fluorophenyl)-1,3-thiazol-2-yl]methyl}methylcarbamate

: 15570-12-4
3-methoxybenzenethiol

: 1138033-77-8
tert-butyl ({4-(2-fluorophenyl)-5-[(3-methoxyphenyl)thio]-1,3-thiazol-2-yl}methyl)methylcarbamate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In toluene; at 110 ℃; for 8h;