(4R,5R)-5-acetyl-3-((S)-2-ethoxy-1-hydroxy-2-oxoethyl)-5-(ethoxycarbonyl)-4-(p-tolyl)-4,5-dihydro isoxazole 2-oxide

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Chemical Name:(4R,5R)-5-acetyl-3-((S)-2-ethoxy-1-hydroxy-2-oxoethyl)-5-(ethoxycarbonyl)-4-(p-tolyl)-4,5-dihydro isoxazole 2-oxide
CAS No.:1412897-07-4
Molecular Formula:C₁₉H₂₃NO₈
Molecular Weight:393.394
Hs Code.:

Synonyms:(4R,5R)-5-acetyl-3-((S)-2-ethoxy-1-hydroxy-2-oxoethyl)-5-(ethoxycarbonyl)-4-(p-tolyl)-4,5-dihydro isoxazole 2-oxide

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Chemical Property of (4R,5R)-5-acetyl-3-((S)-2-ethoxy-1-hydroxy-2-oxoethyl)-5-(ethoxycarbonyl)-4-(p-tolyl)-4,5-dihydro isoxazole 2-oxide

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Technology Process of (4R,5R)-5-acetyl-3-((S)-2-ethoxy-1-hydroxy-2-oxoethyl)-5-(ethoxycarbonyl)-4-(p-tolyl)-4,5-dihydro isoxazole 2-oxide

There total 1 articles about (4R,5R)-5-acetyl-3-((S)-2-ethoxy-1-hydroxy-2-oxoethyl)-5-(ethoxycarbonyl)-4-(p-tolyl)-4,5-dihydro isoxazole 2-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: C₁₃H₁₅NO₅

: 609-15-4
ethyl 2-chloro-3-oxo-butyrate

: 1412897-07-4
(4R,5R)-5-acetyl-3-((S)-2-ethoxy-1-hydroxy-2-oxoethyl)-5-(ethoxycarbonyl)-4-(p-tolyl)-4,5-dihydro isoxazole 2-oxide

Guidance literature:: With quinindine; In dichloromethane; at -78 ℃; for 72h; enantioselective reaction; Inert atmosphere;
DOI:10.1039/c2ob26165k DOI:10.1039/c2ob26165k