malonic acid ethyl ester 12-(toluene-4-sulfonyloxy)-dodecyl ester

Base Information

• Chemical Name: malonic acid ethyl ester 12-(toluene-4-sulfonyloxy)-dodecyl ester
• CAS No.: 643026-32-8
• Molecular Formula: C₂₄H₃₈O₇S
• Molecular Weight: 470.628
• Mol file: 643026-32-8.mol

Synonyms:malonic acid ethyl ester 12-(toluene-4-sulfonyloxy)-dodecyl ester

Chemical Property of malonic acid ethyl ester 12-(toluene-4-sulfonyloxy)-dodecyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of malonic acid ethyl ester 12-(toluene-4-sulfonyloxy)-dodecyl ester

There total 3 articles about malonic acid ethyl ester 12-(toluene-4-sulfonyloxy)-dodecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

ethyl chlorocarbonylacetate (36239-09-5) + 1,12-dodecanediol mono(4-methylbenzenesulfonate) (643026-30-6) → malonic acid ethyl ester 12-(toluene-4-sulfonyloxy)-dodecyl ester (643026-32-8)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tetlet.2003.09.198

Reference yield:

1,12-dodecandiol (5675-51-4) → malonic acid ethyl ester 12-(toluene-4-sulfonyloxy)-dodecyl ester (643026-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 44 percent / triethylamine / CH₂Cl₂ / 20 °C

2: 78 percent / triethylamine / CH₂Cl₂ / 20 °C

With triethylamine; In dichloromethane;

DOI:10.1016/j.tetlet.2003.09.198

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → malonic acid ethyl ester 12-(toluene-4-sulfonyloxy)-dodecyl ester (643026-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 44 percent / triethylamine / CH₂Cl₂ / 20 °C

2: 78 percent / triethylamine / CH₂Cl₂ / 20 °C

With triethylamine; In dichloromethane;

DOI:10.1016/j.tetlet.2003.09.198

upstream raw materials:

ethyl chlorocarbonylacetate

1,12-dodecanediol mono(4-methylbenzenesulfonate)

1,12-dodecandiol

p-toluenesulfonyl chloride