C₄₈H₆₅O₈PSi₂

Base Information

• Chemical Name: C₄₈H₆₅O₈PSi₂
• CAS No.: 1028432-58-7
• Molecular Formula: C₄₈H₆₅O₈PSi₂
• Molecular Weight: 857.184
• Mol file: 1028432-58-7.mol

Synonyms:C₄₈H₆₅O₈PSi₂

Chemical Property of C₄₈H₆₅O₈PSi₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₈H₆₅O₈PSi₂

There total 15 articles about C₄₈H₆₅O₈PSi₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C36H56O5Si2 (1028432-77-0) + chlorophosphoric acid diphenyl ester (2524-64-3) → C48H65O8PSi2 (1028432-58-7)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hexamethylsilazane; In tetrahydrofuran; toluene; at -78 ℃; for 0.75h; Inert atmosphere;

DOI:10.1021/ol800685c

Reference yield:

C36H60O5Si2 (1028432-76-9) → C48H65O8PSi2 (1028432-58-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 2,2,6,6-tetramethyl-piperidine-N-oxyl; [bis(acetoxy)iodo]benzene / dichloromethane / 20 °C

2: N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hexamethylsilazane / tetrahydrofuran; toluene / 0.75 h / -78 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; 2,2,6,6-tetramethyl-piperidine-N-oxyl; [bis(acetoxy)iodo]benzene; potassium hexamethylsilazane; In tetrahydrofuran; dichloromethane; toluene;

DOI:10.1002/chem.201101437

Reference yield:

C30H40O5Si (1360872-90-7) → C48H65O8PSi2 (1028432-58-7)

Guidance literature:

Multi-step reaction with 14 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C

1.2: 3 h / -78 - 20 °C

2.1: copper(l) iodide / tetrahydrofuran; diethyl ether / 0.17 h / -40 °C

2.2: 0.75 h / -40 °C

3.1: Dess-Martin periodane / dichloromethane / 0 - 20 °C

4.1: tetrahydrofuran; diethyl ether / 0.5 h / -78 °C

5.1: 2,6-dimethylpyridine / dichloromethane / 4.5 h / 20 °C

6.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 3 h / 20 °C

6.2: 1 h / 20 °C

7.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0 - 20 °C / pH 7 / aq. phosphate buffer

8.1: 2,2,6,6-tetramethyl-piperidine-N-oxyl; [bis(acetoxy)iodo]benzene / dichloromethane / 20 °C

9.1: N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hexamethylsilazane / tetrahydrofuran; toluene / 0.5 h / -78 °C

10.1: caesium carbonate / tetrahydrofuran; water / 0.25 h / 20 °C

10.2: 16.25 h / 50 °C

11.1: 2,3-Dimethyl-2-butene; dimethylsulfide borane complex / tetrahydrofuran / 0 - 20 °C

11.2: 0 - 20 °C

12.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0 - 20 °C / pH 7 / aq. phosphate buffer

13.1: 2,2,6,6-tetramethyl-piperidine-N-oxyl; [bis(acetoxy)iodo]benzene / dichloromethane / 20 °C

14.1: N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hexamethylsilazane / tetrahydrofuran; toluene / 0.75 h / -78 °C

With 2,6-dimethylpyridine; N,N,N,N,N,N-hexamethylphosphoric triamide; 2,2,6,6-tetramethyl-piperidine-N-oxyl; copper(l) iodide; 2,3-Dimethyl-2-butene; [bis(acetoxy)iodo]benzene; dimethylsulfide borane complex; potassium hexamethylsilazane; sodium hydride; caesium carbonate; Dess-Martin periodane; 9-bora-bicyclo[3.3.1]nonane; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; diethyl ether; dichloromethane; water; toluene; mineral oil; 10.1: Suzuki-Miyaura coupling / 10.2: Suzuki-Miyaura coupling;

DOI:10.1002/chem.201101437

upstream raw materials:

C₃₆H₅₆O₅Si₂

chlorophosphoric acid diphenyl ester

C₃₆H₆₀O₅Si₂

C₃₀H₄₀O₅Si

Downstream raw materials:

C₇₆H₁₀₈O₁₃Si₂

C₆₂H₉₆O₁₁Si₂