(2R,3R,4S,5S,6S)--3,5--dimethyl--2,6--diphenyltetrahydro--2H--pyran--4--ol

Base Information

Chemical Name:(2R,3R,4S,5S,6S)--3,5--dimethyl--2,6--diphenyltetrahydro--2H--pyran--4--ol
CAS No.:69291-50-5
Molecular Formula:C₁₉H₂₂O₂
Molecular Weight:282.382
Hs Code.:

Synonyms:(2R,3R,4S,5S,6S)--3,5--dimethyl--2,6--diphenyltetrahydro--2H--pyran--4--ol

Suppliers and Price of (2R,3R,4S,5S,6S)--3,5--dimethyl--2,6--diphenyltetrahydro--2H--pyran--4--ol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3R,4S,5S,6S)--3,5--dimethyl--2,6--diphenyltetrahydro--2H--pyran--4--ol

Chemical Property:

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Technology Process of (2R,3R,4S,5S,6S)--3,5--dimethyl--2,6--diphenyltetrahydro--2H--pyran--4--ol

There total 2 articles about (2R,3R,4S,5S,6S)--3,5--dimethyl--2,6--diphenyltetrahydro--2H--pyran--4--ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: C₁₀H₁₉BO₂

: 100-52-7
benzaldehyde

: 69291-50-5
(2R,3R,4S,5S,6S)--3,5--dimethyl--2,6--diphenyltetrahydro--2H--pyran--4--ol

Guidance literature:: C₁₀H₁₉BO₂; With boron trifluoride diethyl etherate; In dichloromethane; at 20 ℃; for 0.75h;

benzaldehyde; In dichloromethane; at -78 - 20 ℃; for 7h;

With water; In dichloromethane; for 3h;
DOI:10.1016/j.tetlet.2012.10.091

Reference yield:

: C₁₀H₁₉BO₂

: 100-52-7
benzaldehyde

: 2043-61-0
cyclohexanecarbaldehyde

: 1416228-47-1
(2S,3R,4R,5S,6S)--2--cyclohexyl--3,5--dimethyl--6--phenyltetrahydro--2H--pyran--4--ol

: 69291-50-5
(2R,3R,4S,5S,6S)--3,5--dimethyl--2,6--diphenyltetrahydro--2H--pyran--4--ol

Guidance literature:: With boron trifluoride diethyl etherate; In dichloromethane; at -78 ℃; for 6h; Overall yield = 54%; Overall yield = 108 mg;
DOI:10.1016/j.tetlet.2012.10.091