(Z)-1-(3-Hydroxy-3-methyl-1-butenyl)-2,6,6-trimethyl-2-cyclohexen-1-ol

Base Information

• Chemical Name: (Z)-1-(3-Hydroxy-3-methyl-1-butenyl)-2,6,6-trimethyl-2-cyclohexen-1-ol
• CAS No.: 113831-83-7
• Molecular Formula: C₁₄H₂₄O₂
• Molecular Weight: 224.343
• Mol file: 113831-83-7.mol

Synonyms:(Z)-1-(3-Hydroxy-3-methyl-1-butenyl)-2,6,6-trimethyl-2-cyclohexen-1-ol

Chemical Property of (Z)-1-(3-Hydroxy-3-methyl-1-butenyl)-2,6,6-trimethyl-2-cyclohexen-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-1-(3-Hydroxy-3-methyl-1-butenyl)-2,6,6-trimethyl-2-cyclohexen-1-ol

There total 6 articles about (Z)-1-(3-Hydroxy-3-methyl-1-butenyl)-2,6,6-trimethyl-2-cyclohexen-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

methyllithium (917-54-4) + 6,10,10-Trimethyl-1-oxaspiro<4.5>deca-3,6-dien-2-on (113832-48-7) → (Z)-1-(3-Hydroxy-3-methyl-1-butenyl)-2,6,6-trimethyl-2-cyclohexen-1-ol (113831-83-7)

Guidance literature:

In diethyl ether; for 12h;

Reference yield: 92.0%

1-(3-Hydroxy-3-methyl-1-butinyl)-2,6,6-trimethyl-2-cyclohexen-1-ol (113831-76-8) → (Z)-1-(3-Hydroxy-3-methyl-1-butenyl)-2,6,6-trimethyl-2-cyclohexen-1-ol (113831-83-7)

Guidance literature:

With hydrogen; Pd-BaSO₄; 10% Pd-BaSO4; In ethanol;

Reference yield:

2,6,6-trimethylcyclohex-2-en-1-one (20013-73-4) → (Z)-1-(3-Hydroxy-3-methyl-1-butenyl)-2,6,6-trimethyl-2-cyclohexen-1-ol (113831-83-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Mg, EtBr / 1.) THF, 1 h, 20 deg C, 2.) THF, 12 h, reflux

2: 92 percent / H₂ / Pd/BaSO₄ (10percent Pd) / ethanol

With hydrogen; ethidium Bromide; magnesium; Pd-BaSO₄; 10% Pd-BaSO4; In ethanol;

upstream raw materials:

methyllithium

6,10,10-Trimethyl-1-oxaspiro<4.5>deca-3,6-dien-2-on

1-(3-Hydroxy-3-methyl-1-butinyl)-2,6,6-trimethyl-2-cyclohexen-1-ol

methyl iodide