3-(tert-butyl)-5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole

Base Information

• Chemical Name: 3-(tert-butyl)-5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole
• CAS No.: 1430730-68-9
• Molecular Formula: C₄₀H₃₇N₃O₉
• Molecular Weight: 703.748
• Mol file: 1430730-68-9.mol

Synonyms:3-(tert-butyl)-5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole

Chemical Property of 3-(tert-butyl)-5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(tert-butyl)-5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole

There total 4 articles about 3-(tert-butyl)-5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

N4-(pivaloyl)-N1-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone (1430730-67-8) → 3-(tert-butyl)-5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole (1430730-68-9)

Guidance literature:

In 5,5-dimethyl-1,3-cyclohexadiene; at 120 ℃; for 2h;

Reference yield:

N1-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone (1430730-32-7) → 3-(tert-butyl)-5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole (1430730-68-9)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine; dmap / chloroform / 20 °C / Reflux

2: 5,5-dimethyl-1,3-cyclohexadiene / 2 h / 120 °C

With pyridine; dmap; In 5,5-dimethyl-1,3-cyclohexadiene; chloroform;

Reference yield:

ethyl C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formimidate (1430730-28-1) → 3-(tert-butyl)-5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole (1430730-68-9)

Guidance literature:

Multi-step reaction with 3 steps

1: dichloromethane / 72 h / 20 °C

2: pyridine; dmap / chloroform / 20 °C / Reflux

3: 5,5-dimethyl-1,3-cyclohexadiene / 2 h / 120 °C

With pyridine; dmap; In 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane; chloroform;

upstream raw materials:

N¹-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone

N⁴-(pivaloyl)-N¹-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone

2,6-anhydro-3,4,5,7-tetra-O-benzoyl-D-glycero-D-gulo-heptonamide

ethyl C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formimidate