1,3,5-tris[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2,4,6-triethylbenzene

Base Information

• Chemical Name: 1,3,5-tris[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2,4,6-triethylbenzene
• CAS No.: 436084-62-7
• Molecular Formula: C₃₀H₃₉Br₃N₆
• Molecular Weight: 723.392
• Mol file: 436084-62-7.mol

Synonyms:1,3,5-tris[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2,4,6-triethylbenzene

Chemical Property of 1,3,5-tris[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2,4,6-triethylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3,5-tris[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2,4,6-triethylbenzene

There total 4 articles about 1,3,5-tris[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2,4,6-triethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1,3,5-tris[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2,4,6-triethylbenzene → 1,3,5-tris[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2,4,6-triethylbenzene (436084-62-7)

Guidance literature:

With bromine; In chloroform; at 0 ℃; for 1h;

DOI:10.1021/ja0174175

Reference yield: 85.0%

4-Bromo-3,5-dimethylpyrazole (3398-16-1) + 1,3,5-tris(bromomethyl)-2,4,6-triethylbenzene (181058-08-2) → 1,3,5-tris[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2,4,6-triethylbenzene (436084-62-7)

Guidance literature:

4-Bromo-3,5-dimethylpyrazole; With sodium hydroxide; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

1,3,5-tris(bromomethyl)-2,4,6-triethylbenzene; In N,N-dimethyl-formamide; at 70 ℃; for 24h;

DOI:10.1055/s-0033-1338518

Reference yield:

3,5-dimethyl-1H-pyrazole (67-51-6) → 1,3,5-tris[(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)methyl]-2,4,6-triethylbenzene (436084-62-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaH / tetrahydrofuran / 0.33 h / 20 °C

1.2: 73 percent / tetrahydrofuran / 3 h

2.1: 97 percent / Br₂ / CHCl₃ / 1 h / 0 °C

With bromine; sodium hydride; In tetrahydrofuran; chloroform;

DOI:10.1021/ja0174175

upstream raw materials:

3,5-dimethyl-1H-pyrazole

1,3,5-tris(bromomethyl)-2,4,6-triethylbenzene

4-Bromo-3,5-dimethylpyrazole