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3398-16-1 Usage

Chemical Properties

white crystalline powder

Check Digit Verification of cas no

The CAS Registry Mumber 3398-16-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,9 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3398-16:
101 % 10 = 1
So 3398-16-1 is a valid CAS Registry Number.

3398-16-1 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (A11759)  4-Bromo-3,5-dimethyl-1H-pyrazole, 98%   

  • 3398-16-1

  • 5g

  • 308.0CNY

  • Detail
  • Alfa Aesar

  • (A11759)  4-Bromo-3,5-dimethyl-1H-pyrazole, 98%   

  • 3398-16-1

  • 25g

  • 1373.0CNY

  • Detail
  • Alfa Aesar

  • (A11759)  4-Bromo-3,5-dimethyl-1H-pyrazole, 98%   

  • 3398-16-1

  • 100g

  • 4536.0CNY

  • Detail
  • Aldrich

  • (B64407)  4-Bromo-3,5-dimethylpyrazole  99%

  • 3398-16-1

  • B64407-1G

  • 237.51CNY

  • Detail
  • Aldrich

  • (B64407)  4-Bromo-3,5-dimethylpyrazole  99%

  • 3398-16-1

  • B64407-10G

  • 1,074.06CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017


1.1 GHS Product identifier

Product name 4-bromo-3,5-dimethyl-1H-pyrazole

1.2 Other means of identification

Product number -
Other names 4-Bromo-3,5-dimethylpyrazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3398-16-1 SDS

3398-16-1Relevant articles and documents

Tumor microenvironment and NIR laser dual-responsive release of berberine 9-: O -pyrazole alkyl derivative loaded in graphene oxide nanosheets for chemo-photothermal synergetic cancer therapy

Cai, Shundong,Du, Peifang,Liu, Yanfei,Liu, Zhenbao,Long, Shuo,Peng, Dongming,Wang, Yirong,Wen, Nachuan,Xiong, Hongjie,Yan, Jianhua

, p. 4046 - 4055 (2020)

A berberine 9-O-pyrazole alkyl derivative, a chemical compound (called B3) previously synthesized by our group, shows anti-cancer activity. However, B3 lacks targeting cytotoxicity to cancer cells, leading to obvious toxic side effects on normal cells. To solve this problem, here, we prepared a drug delivery system, namely, AS1411-GO/B3 for tumor targeting, in which nano-graphene oxide (GO) sheets were employed as the drug carrier, and the aptamer AS1411 was conjugated onto GO for tumor targeting. GO also had a photothermal effect, which helped the release of B3 from GO as well as the thermal cytotoxicity to cells. We found that the release of B3 could respond to acid conditions, indicating that the tumor intracellular environment could promote the release of B3, thus allowing it to perform chemotherapy effects. This system could also release B3 in response to photothermal heating, moreover, combined photothermal therapy and chemotherapy to improve the anticancer activity was achieved. This AS1411-GO/B3 platform with chemo-photothermal synergetic therapy provides a very promising treatment for tumors.

Identification of Isoform 2 Acid-Sensing Ion Channel Inhibitors as Tool Compounds for Target Validation Studies in CNS

Bencheva, Leda Ivanova,De Matteo, Marilenia,Ferrante, Luca,Ferrara, Marco,Prandi, Adolfo,Randazzo, Pietro,Ronzoni, Silvano,Sinisi, Roberta,Seneci, Pierfausto,Summa, Vincenzo,Gallo, Mariana,Veneziano, Maria,Cellucci, Antonella,Mazzocchi, Nausicaa,Menegon, Andrea,Di Fabio, Romano

supporting information, p. 627 - 632 (2019/03/07)

Acid-sensing ion channels (ASICs) are a family of ion channels permeable to cations and largely responsible for the onset of acid-evoked ion currents both in neurons and in different types of cancer cells, thus representing a potential target for drug discovery. Owing to the limited attention ASIC2 has received so far, an exploratory program was initiated to identify ASIC2 inhibitors using diminazene, a known pan-ASIC inhibitor, as a chemical starting point for structural elaboration. The performed exploration enabled the identification of a novel series of ASIC2 inhibitors. In particular, compound 2u is a brain penetrant ASIC2 inhibitor endowed with an optimal pharmacokinetic profile. This compound may represent a useful tool to validate in animal models in vivo the role of ASIC2 in different neurodegenerative central nervous system pathologies.

A two-valence sulfonyl isoxazole derivatives and use thereof


, (2017/10/07)

The invention discloses a bi-titer sulfonyl isoxazole derivative in the technical field of organic compound weedicides, and application thereof. The bi-titer sulfonyl isoxazole derivative has a molecular structural formula shown as a general formula I. The invention further discloses a preparation method of the bi-titer sulfonyl isoxazole derivative. The bi-titer sulfonyl isoxazole derivative has very high activity of inhibiting weed growth and killing and removing weeds, and can be used in agricultural production, and is classified as a novel active component for weedicides.

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