Technology Process of 2β-(4'-(methoxycarbonyl)but-3'-enyl)-3β-phenyltropane
There total 8 articles about 2β-(4'-(methoxycarbonyl)but-3'-enyl)-3β-phenyltropane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: H2 / 10percent Pd/C / methanol / 99 h / 760 Torr
2: 99 percent / LiAlH4 / diethyl ether / Ambient temperature
3: 1) oxalyl chloride, 2.) triethylamine / 1.) CH2Cl2, DMSO, -60 deg C, 1 h, 2.) CH2Cl2, DMSO, -60 deg C - RT
4: lithium chloride, N,N-diisopropylethylamine / acetonitrile / 24 h / Ambient temperature
With
lithium aluminium tetrahydride; oxalyl dichloride; hydrogen; triethylamine; N-ethyl-N,N-diisopropylamine; lithium chloride;
palladium on activated charcoal;
In
methanol; diethyl ether; acetonitrile;
DOI:10.1021/jm960739c
- Guidance literature:
-
Multi-step reaction with 5 steps
1: lithium chloride, N,N-diisopropylethylamine / acetonitrile / 24 h / 25 °C
2: H2 / 10percent Pd/C / methanol / 99 h / 760 Torr
3: 99 percent / LiAlH4 / diethyl ether / Ambient temperature
4: 1) oxalyl chloride, 2.) triethylamine / 1.) CH2Cl2, DMSO, -60 deg C, 1 h, 2.) CH2Cl2, DMSO, -60 deg C - RT
5: lithium chloride, N,N-diisopropylethylamine / acetonitrile / 24 h / Ambient temperature
With
lithium aluminium tetrahydride; oxalyl dichloride; hydrogen; triethylamine; N-ethyl-N,N-diisopropylamine; lithium chloride;
palladium on activated charcoal;
In
methanol; diethyl ether; acetonitrile;
DOI:10.1021/jm960739c
- Guidance literature:
-
With
N-ethyl-N,N-diisopropylamine; lithium chloride;
In
acetonitrile;
at 25 ℃;
DOI:10.1021/jm00049a004
