Trimethyl phosphonoacetate

Base Information Edit

Chemical Name:Trimethyl phosphonoacetate
CAS No.:5927-18-4
Deprecated CAS:51298-31-8
Molecular Formula:C5H11O5P
Molecular Weight:182.113
Hs Code.:29310095
European Community (EC) Number:227-663-0
NSC Number:84262
DSSTox Substance ID:DTXSID3064063
Nikkaji Number:J227E
Wikidata:Q72514300
Metabolomics Workbench ID:67947
Mol file:5927-18-4.mol

Synonyms:trimethylacetyl phosphate

Suppliers and Price of Trimethyl phosphonoacetate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
TmpA
100ug
$ 382.00

TRC
Trimethyl Phosphonoacetate
100g
$ 1320.00

TCI Chemical
Trimethyl Phosphonoacetate >96.0%(GC)
250g
$ 222.00

TCI Chemical
Trimethyl Phosphonoacetate >96.0%(GC)
25g
$ 47.00

Sigma-Aldrich
Trimethyl phosphonoacetate 98%
25g
$ 46.50

Sigma-Aldrich
Trimethyl phosphonoacetate 98%
100g
$ 125.00

Oakwood
Trimethyl Phosphonoacetate 98%
500g
$ 150.00

Medical Isotopes, Inc.
Trimethyl Phosphonoacetate
100 g
$ 2200.00

Matrix Scientific
Methyl 2-(dimethoxyphosphoryl)acetate 98%
500g
$ 232.00

Matrix Scientific
Methyl 2-(dimethoxyphosphoryl)acetate 98%
100g
$ 73.00

Total 143 raw suppliers

Chemical Property of Trimethyl phosphonoacetate Edit

Chemical Property:

Appearance/Colour:clear colorless to light yellow liquid
Vapor Pressure:0.000577mmHg at 25°C
Melting Point:242 °C
Refractive Index:n20/D 1.437(lit.)
Boiling Point:311 ºC at 760 mmHg
Flash Point:109.7 °C
PSA：71.64000
Density:1.125 g/cm³
LogP:0.64530
Storage Temp.:Store below +30°C.
Water Solubility.:Slightly miscible with water.
XLogP3:-0.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:182.03441044
Heavy Atom Count:11
Complexity:170

Purity/Quality:

99% ^*data from raw suppliers

TmpA ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 23-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CP(=O)(OC)OC
Uses Trimethyl phosphonoacetate is used in the preparation of sarin A by intramolecular Mannich-type reactions. It is involved in the Horner-Wadsworth-Emmons olefination with aldehydes and ketones to give acrylic esters. It is also involved in oxa-Michael reactions, prenylation of oxindoles and heterocyclization reactions.

Technology Process of Trimethyl phosphonoacetate

There total 9 articles about Trimethyl phosphonoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%