(4E)-4-[(4-chlorophenyl)methylidene]-3-cyclohexyl-2-cyclohexyliminooxazolidine

Base Information

Chemical Name:(4E)-4-[(4-chlorophenyl)methylidene]-3-cyclohexyl-2-cyclohexyliminooxazolidine
CAS No.:37614-54-3
Molecular Formula:C₂₂H₂₉ClN₂O
Molecular Weight:372.938
Hs Code.:

Synonyms:(4E)-4-[(4-chlorophenyl)methylidene]-3-cyclohexyl-2-cyclohexyliminooxazolidine

Suppliers and Price of (4E)-4-[(4-chlorophenyl)methylidene]-3-cyclohexyl-2-cyclohexyliminooxazolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4E)-4-[(4-chlorophenyl)methylidene]-3-cyclohexyl-2-cyclohexyliminooxazolidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4E)-4-[(4-chlorophenyl)methylidene]-3-cyclohexyl-2-cyclohexyliminooxazolidine

There total 4 articles about (4E)-4-[(4-chlorophenyl)methylidene]-3-cyclohexyl-2-cyclohexyliminooxazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: (Z)-2-bromo-3-(4-chlorophenyl)prop-2-en-1-ol

: 538-75-0
dicyclohexyl-carbodiimide

: 37614-54-3
(4E)-4-[(4-chlorophenyl)methylidene]-3-cyclohexyl-2-cyclohexyliminooxazolidine

Guidance literature:: With copper(I) oxide; potassium phosphate; In dimethyl sulfoxide; at 100 ℃; for 24h; diastereoselective reaction; Molecular sieve; Sealed tube; Inert atmosphere;
DOI:10.1016/j.tet.2018.08.051

Reference yield:

: (Z)-2-bromo-3-(4-chlorophenyl)acrylaldehyde

: 37614-54-3
(4E)-4-[(4-chlorophenyl)methylidene]-3-cyclohexyl-2-cyclohexyliminooxazolidine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol; dichloromethane / 0.75 h / 20 °C

2: copper(I) oxide; potassium phosphate / dimethyl sulfoxide / 24 h / 100 °C / Molecular sieve; Sealed tube; Inert atmosphere

With copper(I) oxide; sodium tetrahydroborate; potassium phosphate; In methanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1016/j.tet.2018.08.051

Reference yield:

: 1075-77-0
4-chlorocinnamaldehyde

: 37614-54-3
(4E)-4-[(4-chlorophenyl)methylidene]-3-cyclohexyl-2-cyclohexyliminooxazolidine

Guidance literature:: Multi-step reaction with 3 steps

1.1: bromine / dichloromethane / 0.75 h / 0 °C

1.2: 1.5 h / 0 - 20 °C

2.1: sodium tetrahydroborate / methanol; dichloromethane / 0.75 h / 20 °C

3.1: copper(I) oxide; potassium phosphate / dimethyl sulfoxide / 24 h / 100 °C / Molecular sieve; Sealed tube; Inert atmosphere

With copper(I) oxide; sodium tetrahydroborate; potassium phosphate; bromine; In methanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1016/j.tet.2018.08.051