3-(3,4-Difluorophenyl)-1-propene

Base Information

• Chemical Name: 3-(3,4-Difluorophenyl)-1-propene
• CAS No.: 842124-23-6
• Molecular Formula: C₉H₈F₂
• Molecular Weight: 154.159
• DSSTox Substance ID: DTXSID30374286
• Nikkaji Number: J3.517.356K
• Wikidata: Q82162817
• Mol file: 842124-23-6.mol

Synonyms:3-(3,4-Difluorophenyl)-1-propene;842124-23-6;1,2-difluoro-4-prop-2-enylbenzene;4-allyl-1,2-difluorobenzene;SCHEMBL12833024;DTXSID30374286;MFCD06201186;1-(2-Propenyl)-3,4-difluorobenzene;AKOS006346303;1,2-difluoro-4-(prop-2-en-1-yl)benzene;FT-0692397;J3.517.356K;EN300-698397

Chemical Property of 3-(3,4-Difluorophenyl)-1-propene

Chemical Property:

• Vapor Pressure: 2.61mmHg at 25°C
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 154.05940658
• Heavy Atom Count: 11
• Complexity: 134

Purity/Quality:

98% ^*data from raw suppliers

3-(3,4-DIFLUOROPHENYL)-1-PROPENE ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

Useful:

• Canonical SMILES: C=CCC1=CC(=C(C=C1)F)F

Technology Process of 3-(3,4-Difluorophenyl)-1-propene

There total 1 articles about 3-(3,4-Difluorophenyl)-1-propene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

Allyl acetate (591-87-7) + 1-bromo-3,4-difluorobenzene (348-61-8) → 4-allyl-1,2-difluorobenzene (842124-23-6)

Guidance literature:

1-bromo-3,4-difluorobenzene; With magnesium; lithium chloride; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;

With iron(III)-acetylacetonate; In tetrahydrofuran; at 0 ℃; for 0.0833333h; Inert atmosphere;

Allyl acetate; In tetrahydrofuran; at 0 ℃; for 0.75h; Inert atmosphere;

DOI:10.1002/adsc.201000228

Reference yield: 86.0%

4-allyl-1,2-difluorobenzene (842124-23-6) → 1,2-difluoro-4-propylbenzene

Guidance literature:

With iron(III) chloride; lithium aluminium tetrahydride; hydrogen; In tetrahydrofuran; at 18 ℃; for 18h; under 750.075 Torr; Inert atmosphere; Sealed tube;

DOI:10.1039/c4gc02368d

upstream raw materials:

Allyl acetate

1-bromo-3,4-difluorobenzene

Refernces