4-((4-Hydroxypiperidin-1-yl)methyl)benzonitrile

Base Information

Chemical Name:4-((4-Hydroxypiperidin-1-yl)methyl)benzonitrile
CAS No.:887593-88-6
Molecular Formula:C13H16 N2 O
Molecular Weight:216.283
Hs Code.:
DSSTox Substance ID:DTXSID30456617
Wikidata:Q72481334
Mol file:887593-88-6.mol

Synonyms:887593-88-6;4-((4-Hydroxypiperidin-1-yl)methyl)benzonitrile;4-(4-HYDROXY-PIPERIDIN-1-YLMETHYL)-BENZONITRILE;4-[(4-hydroxypiperidin-1-yl)methyl]benzonitrile;SCHEMBL647375;DTXSID30456617;AKOS000177202;A861471;Z54505510

Suppliers and Price of 4-((4-Hydroxypiperidin-1-yl)methyl)benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
4-(4-hydroxy-piperidin-1-ylmethyl)-benzonitrile 95
10g
$ 2108.00

Chemenu
4-((4-hydroxypiperidin-1-yl)methyl)benzonitrile 95%
1g
$ 296.00

Alichem
4-((4-Hydroxypiperidin-1-yl)methyl)benzonitrile
1g
$ 400.00

Total 11 raw suppliers

Chemical Property of 4-((4-Hydroxypiperidin-1-yl)methyl)benzonitrile

Chemical Property:

PSA：47.26000
Density:1.17
LogP:1.45288
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:216.126263138
Heavy Atom Count:16
Complexity:254

Purity/Quality:

97% ^*data from raw suppliers

4-(4-hydroxy-piperidin-1-ylmethyl)-benzonitrile 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1O)CC2=CC=C(C=C2)C#N

Technology Process of 4-((4-Hydroxypiperidin-1-yl)methyl)benzonitrile

There total 1 articles about 4-((4-Hydroxypiperidin-1-yl)methyl)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 5382-16-1
4-HYDROXYPIPERIDINE

: 17201-43-3
4-cyanobenzyl bromide

: 887593-88-6
1-(4-cyanobenzyl)piperidin-4-ol

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran;
DOI:10.1021/jm020375q

Reference yield: 37.0%

: 1152424-93-5
N-(1-benzylpiperidin-4-yl)-5-hydroxybenzofurancarboxamide

: 887593-88-6
1-(4-cyanobenzyl)piperidin-4-ol

: 1152423-92-1
N-(1-benzylpiperidin-4-yl)-5-(1-(4-cyanobenzyl)piperidin-4-yloxy)benzofuran-2-carboxamide

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In toluene; at 20 - 80 ℃;

Reference yield:

: 887593-88-6
1-(4-cyanobenzyl)piperidin-4-ol

: 1016863-24-3
4-(4-Oxo-piperidin-1-ylmethyl)-benzonitrile

Guidance literature:: With pyridine; dicyclohexyl-carbodiimide; trifluoroacetic acid; In dichloromethane; dimethyl sulfoxide;
DOI:10.1016/0960-894X(96)00373-3