(S,E)-methyl 2-[2-[4-(3-(1H-indol-3-yl)-3-oxoprop-1-enyl)-phenoxy]acetamido]-3-phenylpropanoate

Base Information

Chemical Name:(S,E)-methyl 2-[2-[4-(3-(1H-indol-3-yl)-3-oxoprop-1-enyl)-phenoxy]acetamido]-3-phenylpropanoate
CAS No.:1269423-92-8
Molecular Formula:C₂₉H₂₆N₂O₅
Molecular Weight:482.536
Hs Code.:

Synonyms:(S,E)-methyl 2-[2-[4-(3-(1H-indol-3-yl)-3-oxoprop-1-enyl)-phenoxy]acetamido]-3-phenylpropanoate

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Chemical Property of (S,E)-methyl 2-[2-[4-(3-(1H-indol-3-yl)-3-oxoprop-1-enyl)-phenoxy]acetamido]-3-phenylpropanoate

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Technology Process of (S,E)-methyl 2-[2-[4-(3-(1H-indol-3-yl)-3-oxoprop-1-enyl)-phenoxy]acetamido]-3-phenylpropanoate

There total 1 articles about (S,E)-methyl 2-[2-[4-(3-(1H-indol-3-yl)-3-oxoprop-1-enyl)-phenoxy]acetamido]-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1269423-90-6
{4-[(1E)-3-(1H-indol-3-yl)-3-oxoprop-1-en-1-yl]phenoxy}acetic acid

: 2577-90-4
methyl (2S)-2-amino-3-phenylpropanoate

: 1269423-92-8
(S,E)-methyl 2-[2-[4-(3-(1H-indol-3-yl)-3-oxoprop-1-enyl)-phenoxy]acetamido]-3-phenylpropanoate

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 18h;
DOI:10.1016/j.bmc.2010.11.017

Reference yield: 88.0%

: 1269423-92-8
(S,E)-methyl 2-[2-[4-(3-(1H-indol-3-yl)-3-oxoprop-1-enyl)-phenoxy]acetamido]-3-phenylpropanoate

: 1269423-80-4
(S,E)-2-[2-[4-(3-(1H-indol-3-yl)-3-oxoprop-1-enyl)-phenoxy]acetamido]-3-phenylpropanoic acid

Guidance literature:: (S,E)-methyl 2-[2-[4-(3-(1H-indol-3-yl)-3-oxoprop-1-enyl)-phenoxy]acetamido]-3-phenylpropanoate; With water; lithium hydroxide; In tetrahydrofuran; ethanol; at 20 - 25 ℃; for 3h;

With hydrogenchloride; In tetrahydrofuran; ethanol; water; ethyl acetate;
DOI:10.1016/j.bmc.2010.11.017