C₂₀H₂₀N₈O

Base Information

Chemical Name:C₂₀H₂₀N₈O
CAS No.:1613021-37-6
Molecular Formula:C₂₀H₂₀N₈O
Molecular Weight:388.432
Hs Code.:

C<sub>20</sub>H<sub>20</sub>N<sub>8</sub>O

Synonyms:C₂₀H₂₀N₈O

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₀H₂₀N₈O

Chemical Property:

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Technology Process of C₂₀H₂₀N₈O

There total 8 articles about C₂₀H₂₀N₈O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13061-96-6
dihydroxy-methyl-borane

: 1613023-19-0
N-[(3S)-1-imidazo[1,2-a]pyrazin-8-ylpyrrolidin-3-yl]-1-(4-iodophenyl)-1,2,4-triazole-3-carboxamide

: 1613021-37-6
C₂₀H₂₀N₈O

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; cesium fluoride; In 1,4-dioxane; at 90 ℃; for 2h; Inert atmosphere; Sealed tube;

Reference yield:

: 1613023-17-8
methyl 1-(4-iodophenyl)-1,2,4-triazole-3-carboxylate

: 1613021-37-6
C₂₀H₂₀N₈O

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / methanol; tetrahydrofuran / 2.5 h / 20 - 50 °C

2: oxalyl dichloride; N,N-dimethyl-formamide / 1,2-dichloro-ethane / 0.08 h / 50 °C

3: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.33 h / Reflux

4: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; cesium fluoride / 1,4-dioxane / 2 h / 90 °C / Inert atmosphere; Sealed tube

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; oxalyl dichloride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; cesium fluoride; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; 1,2-dichloro-ethane;

Reference yield:

: 5122-99-6
4-iodophenylboronic acid

: 1613021-37-6
C₂₀H₂₀N₈O

Guidance literature:: Multi-step reaction with 5 steps

1: copper diacetate; pyridine / N,N-dimethyl-formamide / 0.5 h / 90 °C

2: sodium hydroxide / methanol; tetrahydrofuran / 2.5 h / 20 - 50 °C

3: oxalyl dichloride; N,N-dimethyl-formamide / 1,2-dichloro-ethane / 0.08 h / 50 °C

4: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.33 h / Reflux

5: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; cesium fluoride / 1,4-dioxane / 2 h / 90 °C / Inert atmosphere; Sealed tube

With pyridine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; oxalyl dichloride; copper diacetate; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; cesium fluoride; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide;