CYCLOHEXYLMETHYL-(4-TRIFLUOROMETHYL-PHENYL)-AMINE

Base Information

Chemical Name:CYCLOHEXYLMETHYL-(4-TRIFLUOROMETHYL-PHENYL)-AMINE
CAS No.:887590-21-8
Molecular Formula:C₁₄H₁₈F₃N
Molecular Weight:257.299
Hs Code.:
Mol file:887590-21-8.mol

Synonyms:CYCLOHEXYLMETHYL-(4-TRIFLUOROMETHYL-PHENYL)-AMINE

Suppliers and Price of CYCLOHEXYLMETHYL-(4-TRIFLUOROMETHYL-PHENYL)-AMINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
Cyclohexylmethyl-(4-trifluoromethyl-phenyl)-amine 95
5g
$ 1833.00

American Custom Chemicals Corporation
CYCLOHEXYLMETHYL-(4-TRIFLUOROMETHYL-PHENYL)AMINE 95.00%
5MG
$ 496.57

Total 2 raw suppliers

Chemical Property of CYCLOHEXYLMETHYL-(4-TRIFLUOROMETHYL-PHENYL)-AMINE

Chemical Property:

PSA：12.03000
LogP:4.77060

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Cyclohexylmethyl-(4-trifluoromethyl-phenyl)-amine 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of CYCLOHEXYLMETHYL-(4-TRIFLUOROMETHYL-PHENYL)-AMINE

There total 3 articles about CYCLOHEXYLMETHYL-(4-TRIFLUOROMETHYL-PHENYL)-AMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 110-82-7,25012-93-5
cyclohexane

: 22864-65-9
N-methyl-4-(trifluoromethyl)aniline

: 887590-21-8
N-(cyclohexylmethyl)-4-(trifluoromethyl)aniline

Guidance literature:: With tert.-butylhydroperoxide; 3,4,7,8-Tetramethyl-o-phenanthrolin; sodium carbonate; iron(II) chloride; at 140 ℃; for 18h; regioselective reaction; Sealed tube;
DOI:10.1021/acs.joc.9b00625

Reference yield:

: C₈H₆F₃N

: 887590-21-8
N-(cyclohexylmethyl)-4-(trifluoromethyl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / 2 h / 0 °C / Reflux

2: iron(II) chloride; 3,4,7,8-Tetramethyl-o-phenanthrolin; tert.-butylhydroperoxide; sodium carbonate / 18 h / 140 °C / Sealed tube

With tert.-butylhydroperoxide; sodium tetrahydroborate; 3,4,7,8-Tetramethyl-o-phenanthrolin; sodium carbonate; iron(II) chloride;
DOI:10.1021/acs.joc.9b00625

Reference yield:

: 455-14-1
4-trifluoromethylphenylamine

: 887590-21-8
N-(cyclohexylmethyl)-4-(trifluoromethyl)aniline

Guidance literature:: Multi-step reaction with 3 steps

1: sodium; methanol / 2 h / Reflux

2: sodium tetrahydroborate / 2 h / 0 °C / Reflux

3: iron(II) chloride; 3,4,7,8-Tetramethyl-o-phenanthrolin; tert.-butylhydroperoxide; sodium carbonate / 18 h / 140 °C / Sealed tube

With methanol; tert.-butylhydroperoxide; sodium tetrahydroborate; 3,4,7,8-Tetramethyl-o-phenanthrolin; sodium; sodium carbonate; iron(II) chloride;
DOI:10.1021/acs.joc.9b00625