potassium (4-bromobenzoyl)trifluoroborate

Base Information

• Chemical Name: potassium (4-bromobenzoyl)trifluoroborate
• CAS No.: 1622923-44-7
• Molecular Formula: C₇H₄BBrF₃O*K
• Molecular Weight: 290.917
• Mol file: 1622923-44-7.mol

Synonyms:potassium (4-bromobenzoyl)trifluoroborate

Chemical Property of potassium (4-bromobenzoyl)trifluoroborate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of potassium (4-bromobenzoyl)trifluoroborate

There total 5 articles about potassium (4-bromobenzoyl)trifluoroborate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

potassium [(4-bromophenyl)(hydroxy)methyl]trifluoroborate → potassium (4-bromobenzoyl)trifluoroborate (1622923-44-7)

Guidance literature:

With 9-azanoradamantane N-oxyl; acetic acid; sodium nitrite; In acetonitrile; at 20 ℃; for 18h; Sealed tube;

DOI:10.1002/anie.201901748

Reference yield: 74.0%

potassium fluoride (7789-23-3) + 1.4-dibromobenzene (106-37-6) + (ethylthiotrifluoroborate)methane dimethyliminium zwitterion (1622923-36-7) + water (7732-18-5) → potassium (4-bromobenzoyl)trifluoroborate (1622923-44-7)

Guidance literature:

1.4-dibromobenzene; (ethylthiotrifluoroborate)methane dimethyliminium zwitterion; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 2.5h; Inert atmosphere;

potassium fluoride; water; In tetrahydrofuran; hexane; acetone; for 2h;

DOI:10.1021/acs.orglett.1c00305

Reference yield: 71.0%

potassium fluoride (7789-23-3) + 1.4-dibromobenzene (106-37-6) + (ethylthiotrifluoroborate)methane dimethyliminium zwitterion (1622923-36-7) → potassium (4-bromobenzoyl)trifluoroborate (1622923-44-7)

Guidance literature:

1.4-dibromobenzene; (ethylthiotrifluoroborate)methane dimethyliminium zwitterion; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

With acetone; In tetrahydrofuran; hexane; at -78 ℃; for 0.166667h; Inert atmosphere;

potassium fluoride; In tetrahydrofuran; hexane; water; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1002/anie.201403931

upstream raw materials:

potassium fluoride

1.4-dibromobenzene

(ethylthiotrifluoroborate)methane dimethyliminium zwitterion

4-bromo-benzaldehyde

Refernces

• 1、 Schuhmacher, Anne,Ryan, Sarah J.,Bode, Jeffrey W.. "Catalytic Synthesis of Potassium Acyltrifluoroborates (KATs) from Boronic Acids and the Thioimidate KAT Transfer Reagent". . p. 3918 - 3922. Retrieved 2020/12/23.
• 2、 Eroes, Gabor,Kushida, Yo,Bode, Jeffrey W.. "A reagent for the one-step preparation of potassium acyltrifluoroborates (KATs) from aryl- and heteroarylhalides". supporting information. p. 7604 - 7607. Retrieved 2014/08/05.