2-propoxybenzonitrile

Base Information

• Chemical Name: 2-propoxybenzonitrile
• CAS No.: 170703-47-6
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 163.192

Synonyms:2-propoxybenzonitrile

Chemical Property of 2-propoxybenzonitrile

Chemical Property:

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Technology Process of 2-propoxybenzonitrile

There total 1 articles about 2-propoxybenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1-bromo-2-propoxybenzene (54554-81-3) + [14C]copper cyanide (17410-52-5) → 2-propoxybenzonitrile (170703-47-6)

Guidance literature:

In various solvent(s); at 190 ℃; for 1.5h;

DOI:10.1002/jlcr.2580360910

Reference yield: 79.0%

2-propoxybenzonitrile (170703-47-6) → 2-propoxybenzamide

Guidance literature:

With sodium hydroxide; dihydrogen peroxide; In methanol; water; at 60 ℃; for 18h;

DOI:10.1002/jlcr.2580360910

Reference yield: 58.3%

methylmagnesium bromide (75-16-1) + 2-propoxybenzonitrile (170703-47-6) → 2-propoxyacetophenone

Guidance literature:

In diethyl ether; benzene; Ambient temperature;

DOI:10.1002/jlcr.2580360910

upstream raw materials:

1-bromo-2-propoxybenzene

[¹⁴C]copper cyanide

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