2,5-anhydro-6-O-benzoyl-4-O-hexanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal

Base Information

• Chemical Name: 2,5-anhydro-6-O-benzoyl-4-O-hexanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal
• CAS No.: 888026-84-4
• Molecular Formula: C₂₂H₃₀O₁₀S
• Molecular Weight: 486.54
• Mol file: 888026-84-4.mol

Synonyms:2,5-anhydro-6-O-benzoyl-4-O-hexanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal

Chemical Property of 2,5-anhydro-6-O-benzoyl-4-O-hexanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-anhydro-6-O-benzoyl-4-O-hexanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal

There total 3 articles about 2,5-anhydro-6-O-benzoyl-4-O-hexanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2,5-anhydro-4-O-n-hexanoyl-3,6-di-O-methanesulfonyl-D-glucoseethylene acetal (888026-83-3) + Potassium benzoate (582-25-2) → 2,5-anhydro-6-O-benzoyl-4-O-hexanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal (888026-84-4)

Guidance literature:

In N,N-dimethyl-formamide; at 100 ℃; for 12h;

DOI:10.1016/j.bmcl.2006.02.001

Reference yield:

Hexanoyl chloride (142-61-0) → 2,5-anhydro-6-O-benzoyl-4-O-hexanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal (888026-84-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / pyridine / CH₂Cl₂ / 24 h / 0 - 20 °C

2: 86 percent / dimethylformamide / 12 h / 100 °C

With pyridine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2006.02.001

Reference yield:

2,5-anhydro-3,6-di-O-methanesulfonyl-D-glucose ethylene acetal (157506-35-9) → 2,5-anhydro-6-O-benzoyl-4-O-hexanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal (888026-84-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / pyridine / CH₂Cl₂ / 24 h / 0 - 20 °C

2: 86 percent / dimethylformamide / 12 h / 100 °C

With pyridine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2006.02.001

upstream raw materials:

2,5-anhydro-4-O-n-hexanoyl-3,6-di-O-methanesulfonyl-D-glucoseethylene acetal

Potassium benzoate

Hexanoyl chloride

2,5-anhydro-3,6-di-O-methanesulfonyl-D-glucose ethylene acetal

Downstream raw materials:

C₁₉H₂₄N₄O₆

ethyl 2-(5-O-benzoyl-2-deoxy-2-hexanamido-β-D-ribofuranosyl)thiazole-4-carboxylate

2,5-anhydro-6-O-benzoyl-3-deoxy-3-hexanamido-D-allonothioamide

2,5-anhydro-3-azido-6-O-benzoyl-3-deoxy-4-O-hexanoyl-D-allononitrile