4-Nitro-benzoic acid (S)-2-((R)-5-oxo-cyclohex-3-enyl)-propyl ester

Base Information

• Chemical Name: 4-Nitro-benzoic acid (S)-2-((R)-5-oxo-cyclohex-3-enyl)-propyl ester
• CAS No.: 140407-89-2
• Molecular Formula: C₁₆H₁₇NO₅
• Molecular Weight: 303.315
• Mol file: 140407-89-2.mol

Synonyms:4-Nitro-benzoic acid (S)-2-((R)-5-oxo-cyclohex-3-enyl)-propyl ester

Chemical Property of 4-Nitro-benzoic acid (S)-2-((R)-5-oxo-cyclohex-3-enyl)-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 4-Nitro-benzoic acid (S)-2-((R)-5-oxo-cyclohex-3-enyl)-propyl ester

There total 2 articles about 4-Nitro-benzoic acid (S)-2-((R)-5-oxo-cyclohex-3-enyl)-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Nitro-benzoic acid (S)-2-((S)-3-phenoxy-cyclohexa-2,4-dienyl)-propyl ester → 4-Nitro-benzoic acid (S)-2-((R)-5-oxo-cyclohex-3-enyl)-propyl ester (140407-89-2)

Guidance literature:

With water; hydrogen cation; Yield given;

DOI:10.1016/S0040-4039(00)92317-7

Reference yield:

4-nitro-benzoyl chloride (122-04-3) → 4-Nitro-benzoic acid (S)-2-((R)-5-oxo-cyclohex-3-enyl)-propyl ester (140407-89-2)

Guidance literature:

Multi-step reaction with 2 steps

2: H⁽¹⁺⁾, H₂O

With water; hydrogen cation;

DOI:10.1016/S0040-4039(00)92317-7

Reference yield: 95.0%

4-Nitro-benzoic acid (S)-2-((R)-5-oxo-cyclohex-3-enyl)-propyl ester (140407-89-2) → 4-Nitro-benzoic acid (S)-2-((R)-3-oxo-cyclohexyl)-propyl ester (140407-90-5)

Guidance literature:

With hydrogen; Wilkinson's catalyst; at 25 ℃; for 12h; under 760 Torr;

DOI:10.1016/S0040-4039(00)92317-7

upstream raw materials:

4-nitro-benzoyl chloride

Downstream raw materials:

4-Nitro-benzoic acid (S)-2-((R)-3-oxo-cyclohexyl)-propyl ester

(S)-2-((R)-3-Oxo-cyclohexyl)-propionic acid

(R)-3-((S)-2-Hydroxy-1-methyl-ethyl)-cyclohexanone