N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-2-chloro-N-p-tolylbenzamide

Base Information

Chemical Name:N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-2-chloro-N-p-tolylbenzamide
CAS No.:1449029-93-9
Molecular Formula:C₃₂H₃₁ClN₂O₅
Molecular Weight:559.062
Hs Code.:

Synonyms:N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-2-chloro-N-p-tolylbenzamide

Suppliers and Price of N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-2-chloro-N-p-tolylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-2-chloro-N-p-tolylbenzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-2-chloro-N-p-tolylbenzamide

There total 4 articles about N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-2-chloro-N-p-tolylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 18234-41-8
5-(benzyloxy)-4-oxo-4H-pyran-2-carbaldehyde

: 119072-55-8,7188-38-7
tert-butylisonitrile

: 106-49-0,12221-03-3
p-toluidine

: 118-91-2
ortho-chlorobenzoic acid

: 1449029-93-9
N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-2-chloro-N-p-tolylbenzamide

Guidance literature:: 5-(benzyloxy)-4-oxo-4H-pyran-2-carbaldehyde; p-toluidine; In methanol; at 20 ℃; for 0.5h;

tert-butylisonitrile; ortho-chlorobenzoic acid; In methanol; at 20 ℃; for 24h;
DOI:10.1016/j.ejmech.2013.05.049

Reference yield:

: 501-30-4,123712-78-7
5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

: 1449029-93-9
N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-2-chloro-N-p-tolylbenzamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide / methanol; water / 4 h / 60 °C

2.1: manganese(IV) oxide / dichloromethane / 72 h / 20 °C

3.1: methanol / 0.5 h / 20 °C

3.2: 24 h / 20 °C

With manganese(IV) oxide; sodium hydroxide; In methanol; dichloromethane; water; 3.1: |Ugi Condensation / 3.2: |Ugi Condensation;
DOI:10.1016/j.ejmech.2013.05.049

Reference yield:

: 15771-06-9
5-benzyloxy-2-hydroxymethyl-4H-pyran-4-one

: 1449029-93-9
N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-2-chloro-N-p-tolylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: manganese(IV) oxide / dichloromethane / 72 h / 20 °C

2.1: methanol / 0.5 h / 20 °C

2.2: 24 h / 20 °C

With manganese(IV) oxide; In methanol; dichloromethane; 2.1: |Ugi Condensation / 2.2: |Ugi Condensation;
DOI:10.1016/j.ejmech.2013.05.049