18234-41-8

Basic information

• Product Name: 4H-Pyran-2-carboxaldehyde, 4-oxo-5-(phenylmethoxy)-
• CAS NO: 18234-41-8
• Molecular Formula: C13H10O4
• Molecular Weight: 230.22
• Mol File: 18234-41-8.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 4H-Pyran-2-carboxaldehyde, 4-oxo-5-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Pyran-2-carboxaldehyde, 4-oxo-5-(phenylmethoxy)-(18234-41-8)
• EPA Substance Registry System: 4H-Pyran-2-carboxaldehyde, 4-oxo-5-(phenylmethoxy)-(18234-41-8)

Safety Data

• Hazardous Substances Data: 18234-41-8(Hazardous Substances Data)

Usage

Structure

Pyran ring with a carboxaldehyde functional group (at position 2) and a phenylmethoxy group (at position 5)

Functional Groups

Carboxaldehyde (-CHO) group
Phenylmethoxy group (phenyl group attached to a methoxy group)

Usage

Organic synthesis
Medicinal chemistry
Production of pharmaceuticals and agrochemicals

Applications

Building block in pharmaceutical synthesis
Building block in agrochemical synthesis
Flavoring agent in the food industry

Versatility

Intermediate in the synthesis of various organic compounds
Potential biological activities due to its unique structure

Aromatic Properties

Suitable for flavoring due to aromatic characteristics

Upstream product

• 89539-54-8 5-(benzyloxy)-2-(chloromethyl)-4H-pyran-4-one 
• 15771-06-9 5-benzyloxy-2-hydroxymethyl-4H-pyran-4-one 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 501-30-4 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one 

Downstream Products

• 1064077-41-3 5-benzyloxy-2-(2,2,2-trifluoro-1-hydroxy-ethyl)-pyran-4-one 
• 1064076-87-4 5-benzyloxy-2-difluoromethyl-pyran-4-one 
• 1449029-96-2 N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-2-chloro-N-(4-methoxyphenyl)benzamide 
• 1449029-93-9 N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-2-chloro-N-p-tolylbenzamide 
• 1449029-95-1 N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-N-(4-butyl-phenyl)-2-chlorobenzamide 
• 1449029-91-7 N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(tert-butylcarbamoyl)methyl]-N-phenylbenzamide 
• 1449029-97-3 N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(cyclohexylcarbamoyl)methyl]-2-chloro-N-(4-chlorophenyl)benzamide 
• 1449029-90-6 N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(cyclohexylcarbamoyl)methyl]-2-chloro-N-phenylbenzamide 
• 1449029-92-8 N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(cyclohexylcarbamoyl)methyl]-2-chloro-N-p-tolylbenzamide 
• 1449029-98-4 N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(cyclohexylcarbamoyl)methyl]-N-(4-chlorophenyl)benzamide 
• 1449029-94-0 N-[(5-(benzyloxy)-4-oxo-4H-pyran-2-yl)(cyclohexylcarbamoyl)methyl]-N-p-tolylbenzamide 

Relevant articles and documents

Synthesis of novel isoxazole derivatives bearing kojic acid moiety and evaluation of their antimicrobial activity

[Figure not available: see fulltext.] A novel series of 3,5-disubstituted isoxazoles bearing kojic acid moiety were synthesized via Cu(I)-catalyzed 1,3-dipolar cycloaddition reaction of terminal alkynes with nitrile oxide formed in situ from the corresponding hydroximoyl chloride. Structures of the synthesized compounds were characterized using spectroscopic analysis data. Antimicrobial activity of the isoxazole conjugates was determined as MIC values by broth microdilution method against different bacteria: Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Salmonella typhi, and fungi Candida kefyr. The obtained results revealed notable antibacterial and antifungal activities of the compounds.

Hydroxypyridinone derivative of aza-chalcone structure, preparation method and application

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Sonochemical syntheses of xanthene derivatives using zeolite-supported transition metal catalysts in aqueous media

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