(trans)-4-(8-amino-1-bromoimidazol[1,5-a]pyrazin-3-yl)cyclohexyl acetate

Base Information

Chemical Name:(trans)-4-(8-amino-1-bromoimidazol[1,5-a]pyrazin-3-yl)cyclohexyl acetate
CAS No.:1419221-24-1
Molecular Formula:C₁₄H₁₇BrN₄O₂
Molecular Weight:353.219
Hs Code.:

Synonyms:(trans)-4-(8-amino-1-bromoimidazol[1,5-a]pyrazin-3-yl)cyclohexyl acetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (trans)-4-(8-amino-1-bromoimidazol[1,5-a]pyrazin-3-yl)cyclohexyl acetate

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Technology Process of (trans)-4-(8-amino-1-bromoimidazol[1,5-a]pyrazin-3-yl)cyclohexyl acetate

There total 5 articles about (trans)-4-(8-amino-1-bromoimidazol[1,5-a]pyrazin-3-yl)cyclohexyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1419221-23-0
(trans)-4-(1-bromo-8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclohexyl acetate

: 1419221-24-1
(trans)-4-(8-amino-1-bromoimidazol[1,5-a]pyrazin-3-yl)cyclohexyl acetate

Guidance literature:: With ammonia; In isopropyl alcohol; at 110 ℃; under 6000.6 Torr;

Reference yield:

: (trans)-4-(8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclohexyl acetate

: 1419221-24-1
(trans)-4-(8-amino-1-bromoimidazol[1,5-a]pyrazin-3-yl)cyclohexyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: N-Bromosuccinimide / N,N-dimethyl-formamide / 1.5 h / 20 °C

2: ammonia / isopropyl alcohol / 110 °C / 6000.6 Torr

With N-Bromosuccinimide; ammonia; In N,N-dimethyl-formamide; isopropyl alcohol;

Reference yield:

: 1326280-86-7
(trans)-N-((3-chloropyrazin-2-yl)methyl)-4-hydroxycyclohexanecarboxamide

: 1419221-24-1
(trans)-4-(8-amino-1-bromoimidazol[1,5-a]pyrazin-3-yl)cyclohexyl acetate

Guidance literature:: Multi-step reaction with 4 steps

1: dmap; pyridine / 1 h / 20 °C

2: trichlorophosphate; N,N-dimethyl-formamide / acetonitrile / 60 °C

3: N-Bromosuccinimide / N,N-dimethyl-formamide / 1.5 h / 20 °C

4: ammonia / isopropyl alcohol / 110 °C / 6000.6 Torr

With pyridine; dmap; N-Bromosuccinimide; ammonia; N,N-dimethyl-formamide; trichlorophosphate; In N,N-dimethyl-formamide; isopropyl alcohol; acetonitrile;