1,3-Benzenedimethanol,2-amino-5-methyl-a1,a1,a3,a3-tetrakis(trifluoromethyl)-

Base Information

Chemical Name:1,3-Benzenedimethanol,2-amino-5-methyl-a1,a1,a3,a3-tetrakis(trifluoromethyl)-
CAS No.:76220-90-1
Molecular Formula:C13H9 F12 N O2
Molecular Weight:439.1969
Hs Code.:

Synonyms:1,3-Benzenedimethanol,2-amino-5-methyl-a,a,a',a'-tetrakis(trifluoromethyl)- (9CI); NSC 354402

Suppliers and Price of 1,3-Benzenedimethanol,2-amino-5-methyl-a1,a1,a3,a3-tetrakis(trifluoromethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 5 raw suppliers

Chemical Property of 1,3-Benzenedimethanol,2-amino-5-methyl-a1,a1,a3,a3-tetrakis(trifluoromethyl)-

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,3-Benzenedimethanol,2-amino-5-methyl-a1,a1,a3,a3-tetrakis(trifluoromethyl)-

There total 4 articles about 1,3-Benzenedimethanol,2-amino-5-methyl-a1,a1,a3,a3-tetrakis(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 80360-42-5
1,4-dihydro-8-<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>-6-methyl-2,2-dimethyl-4,4-bis(trifluoromethyl)-2H-<3,1>benzoxazine

: 76220-90-1
4-methyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline

Guidance literature:: With sulfuric acid; In water; acetic acid; for 24h; Heating;
DOI:10.1021/jo00345a026

Reference yield:

: 76220-89-8
1,4-dihydro-8-bromo-6-methyl-2,2-dimethyl-4,4-bis(trifluoromethyl)-2H-<3,1>benzoxazine

: 684-16-2
Hexafluoroacetone

: 76220-90-1
4-methyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline

Guidance literature:: With n-butyllithium; Yield given. Multistep reaction;
DOI:10.1021/ja00544a047

Reference yield:

: 76220-89-8
1,4-dihydro-8-bromo-6-methyl-2,2-dimethyl-4,4-bis(trifluoromethyl)-2H-<3,1>benzoxazine

: 76220-90-1
4-methyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-butyllithium / 1.) ether, hexane, -78 deg C, 2.) -78 deg C, 15 min

2: 91 percent / conc. sulfuric acid / acetic acid; H₂O / 24 h / Heating

With n-butyllithium; sulfuric acid; In water; acetic acid;
DOI:10.1021/jo00345a026