3-[4-(2-{2-[2-(4-cyclohepta-2,4,6-trienyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-propan-1-ol

Base Information

• Chemical Name: 3-[4-(2-{2-[2-(4-cyclohepta-2,4,6-trienyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-propan-1-ol
• CAS No.: 764687-71-0
• Molecular Formula: C₂₈H₃₄O₅
• Molecular Weight: 450.575
• Mol file: 764687-71-0.mol

Synonyms:3-[4-(2-{2-[2-(4-cyclohepta-2,4,6-trienyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-propan-1-ol

Chemical Property of 3-[4-(2-{2-[2-(4-cyclohepta-2,4,6-trienyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-propan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[4-(2-{2-[2-(4-cyclohepta-2,4,6-trienyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-propan-1-ol

There total 2 articles about 3-[4-(2-{2-[2-(4-cyclohepta-2,4,6-trienyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

3-(4-hydroxyphenyl)propan-1-ol (10210-17-0) + 7-(4-hydroxyphenyl)-1,3,5-cycloheptatriene (91902-42-0) + triethylene glycol di-(p-toluenesulfonate) (19249-03-7) → 3-{4-[2-(2-{2-[4-(3-hydroxy-propyl)-phenoxy]-ethoxy}-ethoxy)-ethoxy]-phenyl}-propan-1-ol + 1,8-bis[4-(cyclohepta-2,4,6-trien-1-yl)phenoxy]-3,6-dioxaoctane + 3-[4-(2-{2-[2-(4-cyclohepta-2,4,6-trienyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-propan-1-ol (764687-71-0)

Guidance literature:

3-(4-hydroxyphenyl)propan-1-ol; 7-(4-hydroxyphenyl)-1,3,5-cycloheptatriene; With sodium ethanolate; In acetonitrile; at 20 ℃; for 0.5h;

triethylene glycol di-(p-toluenesulfonate); In acetonitrile; for 6h; Heating;

DOI:10.1002/chem.200400243

Reference yield: 50.0%

3-(4-hydroxyphenyl)propan-1-ol (10210-17-0) + 7-(4-hydroxyphenyl)-1,3,5-cycloheptatriene (91902-42-0) + 8-tosyloxy-3,6-dioxaoctanol (77544-68-4) → 3-[4-(2-{2-[2-(4-cyclohepta-2,4,6-trienyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-propan-1-ol (764687-71-0)

Guidance literature:

3-(4-hydroxyphenyl)propan-1-ol; 7-(4-hydroxyphenyl)-1,3,5-cycloheptatriene; With sodium ethanolate; In acetonitrile; at 20 ℃; for 0.5h;

8-tosyloxy-3,6-dioxaoctanol; In acetonitrile; for 6h; Heating;

DOI:10.1002/ejoc.200400607

Reference yield: 91.0%

1-Adamantanecarbonyl chloride (2094-72-6) + 3-[4-(2-{2-[2-(4-cyclohepta-2,4,6-trienyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-propan-1-ol (764687-71-0) → adamantane-1-carboxylic acid 3-[4-(2-{2-[2-(4-cyclohepta-2,4,6-trienyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-propyl ester (764687-73-2)

Guidance literature:

With pyridine; at 75 ℃; for 4h;

DOI:10.1002/chem.200400243

upstream raw materials:

3-(4-hydroxyphenyl)propan-1-ol

7-(4-hydroxyphenyl)-1,3,5-cycloheptatriene

8-tosyloxy-3,6-dioxaoctanol

triethylene glycol di-(p-toluenesulfonate)

Downstream raw materials:

adamantane-1-carboxylic acid 3-[4-(2-{2-[2-(4-cyclohepta-2,4,6-trienyl-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-propyl ester

adamantane-1-carboxylic acid 3-(4-{2-[2-(2-{4-[5-(4-amino-phenyl)-cyclohepta-1,3,6-trienyl]-phenoxy}-ethoxy)-ethoxy]-ethoxy}-phenyl)-propyl ester