3-cyano-2,6-dibromo-4-methylpyridine

Base Information

• Chemical Name: 3-cyano-2,6-dibromo-4-methylpyridine
• CAS No.: 38824-75-8
• Molecular Formula: C₇H₄Br₂N₂
• Molecular Weight: 275.93
• Mol file: 38824-75-8.mol

Synonyms:2,6-dibromo-4-methylpyridine-3-carbonitrile

Chemical Property of 3-cyano-2,6-dibromo-4-methylpyridine

Chemical Property:

Purity/Quality:

95+% ^*data from raw suppliers

2,6-Dibromo-4-methylnicotinonitrile 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-cyano-2,6-dibromo-4-methylpyridine

There total 2 articles about 3-cyano-2,6-dibromo-4-methylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,6-dihydroxy-3-cyano-4-methylpyrimidine (5444-02-0) → 2,6-dibromo-4-methylpyridine-3-carbonitrile (38824-75-8)

Guidance literature:

With phosphorus(V) oxybromide; at 190 ℃; for 2h;

Reference yield:

→ 2,6-dibromo-4-methylpyridine-3-carbonitrile (38824-75-8)

Guidance literature:

2,6-Dihydroxy-4-methylpyridin-3-carbonitril, POBr3;

DOI:10.1039/P19720002506

Reference yield: 80.0%

2,6-dibromo-4-methylpyridine-3-carbonitrile (38824-75-8) → 3-cyano-4-methylpyridine (5444-01-9)

Guidance literature:

With ammonia; water; zinc; In tetrahydrofuran; for 5h; Heating / reflux;

upstream raw materials:

2,6-dihydroxy-3-cyano-4-methylpyrimidine

Downstream raw materials:

3-cyano-4-methylpyridine