5-(tert-butyl-dimethyl-silanyloxy)-2-(3,4-dichloro-phenyl)-pentanoic acid

Base Information

Chemical Name:5-(tert-butyl-dimethyl-silanyloxy)-2-(3,4-dichloro-phenyl)-pentanoic acid
CAS No.:619254-40-9
Molecular Formula:C₁₇H₂₆Cl₂O₃Si
Molecular Weight:377.383
Hs Code.:

Synonyms:5-(tert-butyl-dimethyl-silanyloxy)-2-(3,4-dichloro-phenyl)-pentanoic acid

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Chemical Property of 5-(tert-butyl-dimethyl-silanyloxy)-2-(3,4-dichloro-phenyl)-pentanoic acid

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Technology Process of 5-(tert-butyl-dimethyl-silanyloxy)-2-(3,4-dichloro-phenyl)-pentanoic acid

There total 1 articles about 5-(tert-butyl-dimethyl-silanyloxy)-2-(3,4-dichloro-phenyl)-pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 89031-84-5
3-(tert-butyldimethylsilyloxy)propyl bromide

: 619254-40-9
5-(tert-butyl-dimethyl-silanyloxy)-2-(3,4-dichloro-phenyl)-pentanoic acid

Guidance literature:: 3,4-dichlorophenyl acetic acid; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h;

3-(tert-butyldimethylsilyloxy)propyl bromide; In tetrahydrofuran; at 20 ℃; for 2h;

With ammonium chloride; In tetrahydrofuran; water;

Reference yield: 98.0%

: 170229-79-5
4-methoxy-3-(2-piperidin-1-yl-ethoxy)-phenylamine

: 619254-40-9
5-(tert-butyl-dimethyl-silanyloxy)-2-(3,4-dichloro-phenyl)-pentanoic acid

: 619254-41-0
5-(tert-butyl-dimethyl-silanyloxy)-2-(3,4-dichloro-phenyl)-pentanoic acid [4-methoxy-3-(2-piperidin-1-yl-ethoxy)-phenyl]-amide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 16h;