2-(4'-iodo-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

• Chemical Name: 2-(4'-iodo-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS No.: 1033782-48-7
• Molecular Formula: C₁₈H₂₀BIO₂
• Molecular Weight: 406.071
• Mol file: 1033782-48-7.mol

Synonyms:2-(4'-iodo-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property of 2-(4'-iodo-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-(4'-iodo-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 2 articles about 2-(4'-iodo-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

4,4'-diiodobiphenyl (3001-15-8) + bis(pinacol)diborane (73183-34-3) → 2-(4'-iodo-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1033782-48-7)

Guidance literature:

bis(pinacol)diborane; With potassium ethoxide; C₄₀H₆₂N₄Zn₂; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere; Glovebox; Schlenk technique;

4,4'-diiodobiphenyl; In tetrahydrofuran; at 75 ℃; for 24h; Inert atmosphere; Glovebox; Schlenk technique;

DOI:10.1021/acs.organomet.0c00733

Reference yield: 45.0%

2,3-dimethyl-2,3-butane diol (76-09-5) + 4-(4-bromophenyl)bromobenzene (92-86-4) → 2-(4'-iodo-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1033782-48-7)

Guidance literature:

Multistep reaction.;

DOI:10.1055/s-2008-1042911

Reference yield: 62.0%

2-(4'-iodo-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1033782-48-7) + 1-ethynylpyrene (34993-56-1) → 4,4,5,5-tetramethyl-2-(4'-(pyren-1-ylethynyl)-[1,1'-biphenyl]-4-yl)-1,3,2-dioxaborolane

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; copper(l) iodide; triethylamine; In tetrahydrofuran; at 40 ℃; for 6h; Inert atmosphere;

DOI:10.1002/anie.201507186

upstream raw materials:

2,3-dimethyl-2,3-butane diol

4-(4-bromophenyl)bromobenzene

4,4'-diiodobiphenyl

bis(pinacol)diborane