cyclo<2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-(methylpentanoyl)-(2E,5S,6R,7E)-5-hydroxy-6-methyl-8-phenyl-2,7-octadienoyl-3-chloro-D-tyrosyl>

Base Information

Chemical Name:cyclo<2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-(methylpentanoyl)-(2E,5S,6R,7E)-5-hydroxy-6-methyl-8-phenyl-2,7-octadienoyl-3-chloro-D-tyrosyl>
CAS No.:240428-78-8
Molecular Formula:C₃₅H₄₃ClN₂O₇
Molecular Weight:639.189
Hs Code.:

Synonyms:cyclo<2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-(methylpentanoyl)-(2E,5S,6R,7E)-5-hydroxy-6-methyl-8-phenyl-2,7-octadienoyl-3-chloro-D-tyrosyl>

Suppliers and Price of cyclo<2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-(methylpentanoyl)-(2E,5S,6R,7E)-5-hydroxy-6-methyl-8-phenyl-2,7-octadienoyl-3-chloro-D-tyrosyl>

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of cyclo<2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-(methylpentanoyl)-(2E,5S,6R,7E)-5-hydroxy-6-methyl-8-phenyl-2,7-octadienoyl-3-chloro-D-tyrosyl>

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of cyclo<2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-(methylpentanoyl)-(2E,5S,6R,7E)-5-hydroxy-6-methyl-8-phenyl-2,7-octadienoyl-3-chloro-D-tyrosyl>

There total 9 articles about cyclo<2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-(methylpentanoyl)-(2E,5S,6R,7E)-5-hydroxy-6-methyl-8-phenyl-2,7-octadienoyl-3-chloro-D-tyrosyl> which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (S)-2-(3-Amino-2,2-dimethyl-propionyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-{(E)-3-[(R)-1-carboxy-2-(3-chloro-4-hydroxy-phenyl)-ethylcarbamoyl]-allyl}-2-methyl-4-phenyl-but-3-enyl ester

: 240428-78-8
cyclo<2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-(methylpentanoyl)-(2E,5S,6R,7E)-5-hydroxy-6-methyl-8-phenyl-2,7-octadienoyl-3-chloro-D-tyrosyl>

Guidance literature:: With pentafluorophenyl diphenyl-phosphinate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 25 ℃; Yield given;
DOI:10.1021/jm980706s

Reference yield:

: 162599-96-4
3-chloro-D-tyrosine

: 240428-78-8
cyclo<2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-(methylpentanoyl)-(2E,5S,6R,7E)-5-hydroxy-6-methyl-8-phenyl-2,7-octadienoyl-3-chloro-D-tyrosyl>

Guidance literature:: Multi-step reaction with 3 steps

1: 67 percent / N,O-bis(trimethylsilyl)acetamide / dimethylformamide / 55 - 60 °C

2: trifluoroacetic acid / 3 h / 25 °C

3: N,N-diisopropylethylamine, pentafluorophenyl diphenylphosphinate / dimethylformamide / 25 °C

With N,O-bis-(trimethylsilyl)-acetamide; pentafluorophenyl diphenyl-phosphinate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In N,N-dimethyl-formamide;
DOI:10.1021/jm980706s

Reference yield:

: 212252-91-0
D-(R)-3-(3-chloro-4-methoxyphenyl)alanine

: 240428-78-8
cyclo<2,2-dimethyl-β-alanyl-(2S)-2-hydroxy-4-(methylpentanoyl)-(2E,5S,6R,7E)-5-hydroxy-6-methyl-8-phenyl-2,7-octadienoyl-3-chloro-D-tyrosyl>

Guidance literature:: Multi-step reaction with 4 steps

1: 69 percent / 48 percent aq. HBr, phenol / 6 h / Heating

2: 67 percent / N,O-bis(trimethylsilyl)acetamide / dimethylformamide / 55 - 60 °C

3: trifluoroacetic acid / 3 h / 25 °C

4: N,N-diisopropylethylamine, pentafluorophenyl diphenylphosphinate / dimethylformamide / 25 °C

With N,O-bis-(trimethylsilyl)-acetamide; pentafluorophenyl diphenyl-phosphinate; hydrogen bromide; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; phenol; In N,N-dimethyl-formamide;
DOI:10.1021/jm980706s