1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid,5-methyl-,ethylester(9CI)

Base Information

• Chemical Name: 1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid,5-methyl-,ethylester(9CI)
• CAS No.: 800401-90-5
• Molecular Formula: C₁₁H₁₂N₂O₂
• Molecular Weight: 204.228
• Mol file: 800401-90-5.mol

Synonyms:1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid,5-methyl-,ethylester(9CI)

Chemical Property of 1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid,5-methyl-,ethylester(9CI)

Chemical Property:

• Boiling Point: 371.1±37.0 °C(Predicted)
• PKA: 12.85±0.40(Predicted)
• PSA: 0.00000
• Density: 1.232±0.06 g/cm3(Predicted)
• LogP: 0.00000

Purity/Quality:

97% ^*data from raw suppliers

Ethyl5-methyl-1H-pyrrolo[2,3-c]pyridine-2-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid,5-methyl-,ethylester(9CI)

There total 2 articles about 1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid,5-methyl-,ethylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(2-dimethyl-5-nitropyridin-4-yl)-2-oxopropionic acid ethyl ester → 5-methyl-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ethyl ester (800401-90-5)

Guidance literature:

With iron; ammonium chloride; In tetrahydrofuran; ethanol; water; at 20 ℃; for 2h; Heating / reflux;

Reference yield:

2,4-dimethyl-5-nitropyridine (1074-99-3) → 5-methyl-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ethyl ester (800401-90-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium ethoxide / diethyl ether; ethanol / 0.17 h / 20 °C

1.2: 16 h / 20 °C

2.1: iron; ammonium chloride / tetrahydrofuran; ethanol; water / 2 h / 20 °C / Heating / reflux

With potassium ethoxide; iron; ammonium chloride; In tetrahydrofuran; diethyl ether; ethanol; water;

Reference yield:

5-methyl-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ethyl ester (800401-90-5) → 5-methyl-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid (1-dimethylcarbamoyl-2-(S)-phenylethyl)amide

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide; water / ethanol / 4 h / 55 °C

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / DMF (N,N-dimethyl-formamide) / 16 h / 20 °C

With sodium hydroxide; water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); ethanol;

upstream raw materials:

2,4-dimethyl-5-nitropyridine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 800401-90-5 1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid,5-methyl-,ethylester(9CI)

Send

Send

Metric Ton KG G Pound L ML

Send

Send