3-Fluoro-4-(trifluoromethoxy)benzyl bromide

Base Information

Chemical Name:3-Fluoro-4-(trifluoromethoxy)benzyl bromide
CAS No.:886499-04-3
Molecular Formula:C8H5 Br F4 O
Molecular Weight:273.025
Hs Code.:2909309090
European Community (EC) Number:679-335-5
DSSTox Substance ID:DTXSID80590636
Wikidata:Q82484280
Mol file:886499-04-3.mol

Synonyms:886499-04-3;3-Fluoro-4-(trifluoromethoxy)benzyl bromide;4-(bromomethyl)-2-fluoro-1-(trifluoromethoxy)benzene;SCHEMBL4533966;DTXSID80590636;MFCD06660205;AKOS015853288;JS-4407;3-fluoro-4-trifluoromethoxy benzyl bromide;DB-021873

Suppliers and Price of 3-Fluoro-4-(trifluoromethoxy)benzyl bromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
3-Fluoro-4-(trifluoromethoxy)benzyl bromide
5 g
$ 495.00

Matrix Scientific
3-Fluoro-4-(trifluoromethoxy)benzyl bromide
1g
$ 185.00

Matrix Scientific
3-Fluoro-4-(trifluoromethoxy)benzyl bromide
5g
$ 732.00

CHESS?
SG000693:4-Bromomethyl-2-fluoro-1-trifluoromethoxy-benzene 98
1 g
$ 60.00

Alfa Aesar
3-Fluoro-4-(trifluoromethoxy)benzyl bromide, 97%
1g
$ 253.00

Alfa Aesar
3-Fluoro-4-(trifluoromethoxy)benzyl bromide, 97%
250mg
$ 103.00

Total 8 raw suppliers

Chemical Property of 3-Fluoro-4-(trifluoromethoxy)benzyl bromide

Chemical Property:

Refractive Index:1.4680
PSA：9.23000
LogP:3.61920
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:271.94599
Heavy Atom Count:14
Complexity:185

Purity/Quality:

99% ^*data from raw suppliers

3-Fluoro-4-(trifluoromethoxy)benzyl bromide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1CBr)F)OC(F)(F)F

Technology Process of 3-Fluoro-4-(trifluoromethoxy)benzyl bromide

There total 2 articles about 3-Fluoro-4-(trifluoromethoxy)benzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 886498-99-3
(3-fluoro-4-(trifluoromethoxy)phenyl)methanol

: 886499-04-3
4-(bromomethyl)-2-fluoro-1-(trifluoromethoxy)benzene

Guidance literature:: With N-Bromosuccinimide; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jm1010644

Reference yield:

: 473917-15-6
3-fluoro-4-(trifluoromethoxy)benzaldehyde

: 886499-04-3
4-(bromomethyl)-2-fluoro-1-(trifluoromethoxy)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol / 1 h / 20 °C / Inert atmosphere

2: N-Bromosuccinimide; triphenylphosphine / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

With sodium tetrahydroborate; N-Bromosuccinimide; triphenylphosphine; In methanol; dichloromethane;
DOI:10.1021/jm1010644