(S)-2-(1-Fluoroethyl)-6-(6-methoxy-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole

Base Information

Chemical Name:(S)-2-(1-Fluoroethyl)-6-(6-methoxy-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole
CAS No.:1476848-35-7
Molecular Formula:C₂₅H₁₉FN₄O₃S₂
Molecular Weight:506.581
Hs Code.:

Synonyms:(S)-2-(1-Fluoroethyl)-6-(6-methoxy-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole

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Chemical Property of (S)-2-(1-Fluoroethyl)-6-(6-methoxy-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole

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Technology Process of (S)-2-(1-Fluoroethyl)-6-(6-methoxy-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole

There total 6 articles about (S)-2-(1-Fluoroethyl)-6-(6-methoxy-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 23780-13-4
(2-phenylthiazol-4-yl)methanol

: 1476848-38-0
(S)-2-(2-(1-fluoroethyl)imidazo[2,1-b][1,3,4]thiadiazol-6-yl)-6-methoxybenzofuran-4-ol

: 1476848-35-7
(S)-2-(1-Fluoroethyl)-6-(6-methoxy-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:: With diisopropyl (E)-azodicarboxylate; triphenylphosphine; In tetrahydrofuran;

Reference yield:

: 1476848-37-9
(S)-6-(4-(benzyloxy)-6-methoxybenzofuran-2-yl)-2-(1-fluoroethyl)imidazo[2,1-b][1,3,4]thiadiazole

: 1476848-35-7
(S)-2-(1-Fluoroethyl)-6-(6-methoxy-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: boron trichloride; sodium hydrogencarbonate / dichloromethane; water

2: diisopropyl (E)-azodicarboxylate; triphenylphosphine / tetrahydrofuran

With boron trichloride; sodium hydrogencarbonate; diisopropyl (E)-azodicarboxylate; triphenylphosphine; In tetrahydrofuran; dichloromethane; water;

Reference yield:

: toluene-ethyl acetate

: 1476848-35-7
(S)-2-(1-Fluoroethyl)-6-(6-methoxy-4-((2-phenylthiazol-4-yl)methoxy)benzofuran-2-yl)imidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:: Multi-step reaction with 4 steps

1: N-Bromosuccinimide; sodium hydrogencarbonate / tetrahydrofuran; ethyl acetate

2: dichloromethane; isopropyl alcohol

3: boron trichloride; sodium hydrogencarbonate / dichloromethane; water

4: diisopropyl (E)-azodicarboxylate; triphenylphosphine / tetrahydrofuran

With N-Bromosuccinimide; boron trichloride; sodium hydrogencarbonate; diisopropyl (E)-azodicarboxylate; triphenylphosphine; In tetrahydrofuran; dichloromethane; water; ethyl acetate; isopropyl alcohol;