tributyl{[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methyl}phosphonium bromide

Base Information

Chemical Name:tributyl{[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methyl}phosphonium bromide
CAS No.:957137-31-4
Molecular Formula:Br*C₃₁H₄₂FNP
Molecular Weight:558.557
Hs Code.:

Synonyms:tributyl{[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methyl}phosphonium bromide

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Chemical Property of tributyl{[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methyl}phosphonium bromide

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Technology Process of tributyl{[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methyl}phosphonium bromide

There total 1 articles about tributyl{[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methyl}phosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 998-40-3
tributylphosphine

: 154057-56-4
3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)-quinoline

: 957137-31-4
tributyl{[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methyl}phosphonium bromide

Guidance literature:: In toluene; at 50 ℃; for 0.5h;
DOI:10.1055/s-0031-1290916

Reference yield:

: (2S,4R)-4-(tert-butyldimethylsilyloxy)-6-oxotetrahydro-2H-pyran-2-carboxaldehyde

: 957137-31-4
tributyl{[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methyl}phosphonium bromide

: 1356998-79-2
2-cyclopropyl-4-(4-fluorophenyl)-3-methylquinoline

: 1391833-21-8
(4R,6S)-4-{[tert-butyl(dimethyl)silyl]oxy}-6-{(Z)-2-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]vinyl}tetrahydro-2H-pyran-2-one

: 1391833-12-7
(4R,6S)-4-{[tert-butyl(dimethyl)silyl]oxy}-6-{(E)-2-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]vinyl}tetrahydro-2H-pyran-2-one

: 148516-15-8
(6S)-6-{(E)-2-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]vinyl}-5,6-dihydro-2H-pyran-2-one

Guidance literature:: tributyl{[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methyl}phosphonium bromide; With sodium hexamethyldisilazane; In toluene; at 60 ℃; for 0.166667h; Inert atmosphere;

(2S,4R)-4-(tert-butyldimethylsilyloxy)-6-oxotetrahydro-2H-pyran-2-carboxaldehyde; In toluene; for 0.0166667h; Inert atmosphere;
DOI:10.1055/s-0031-1290916