Technology Process of 4''-[10-(hydroxycarbonyl)decyloxy]phenyl 4-[4'-(2-(R)-octyloxy)-3'-nitrophenyl]benzoate
There total 11 articles about 4''-[10-(hydroxycarbonyl)decyloxy]phenyl 4-[4'-(2-(R)-octyloxy)-3'-nitrophenyl]benzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
In
dichloromethane;
for 13h;
DOI:10.1021/ma010290j
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 90 percent / conc. H2SO4 / CH2Cl2 / 15 h / 20 °C
2: 92 percent / K2CO3 / 18-crown-6 / acetone / 36 h / 60 °C
3: 98 percent / H2 / 10 percent Pd/C / ethyl acetate / 20 °C
4: 72 percent / N,N'-dicyclohexylcarbodiimide; 4-(dimethylamino)pyridine / CH2Cl2 / 24 h / 20 °C
5: 95 percent / trifluoroacetic acid / CH2Cl2 / 13 h
With
dmap; sulfuric acid; hydrogen; potassium carbonate; dicyclohexyl-carbodiimide; trifluoroacetic acid;
palladium on activated charcoal; 18-crown-6 ether;
In
dichloromethane; ethyl acetate; acetone;
DOI:10.1021/ma010290j
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 92 percent / K2CO3 / 18-crown-6 / acetone / 36 h / 60 °C
2: 98 percent / H2 / 10 percent Pd/C / ethyl acetate / 20 °C
3: 72 percent / N,N'-dicyclohexylcarbodiimide; 4-(dimethylamino)pyridine / CH2Cl2 / 24 h / 20 °C
4: 95 percent / trifluoroacetic acid / CH2Cl2 / 13 h
With
dmap; hydrogen; potassium carbonate; dicyclohexyl-carbodiimide; trifluoroacetic acid;
palladium on activated charcoal; 18-crown-6 ether;
In
dichloromethane; ethyl acetate; acetone;
DOI:10.1021/ma010290j