Technology Process of 5-(4-methoxyphenyl)-8-phenyl-5,6,6a,7,8,9-hexahydrophenanthridine
There total 4 articles about 5-(4-methoxyphenyl)-8-phenyl-5,6,6a,7,8,9-hexahydrophenanthridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tris-(dibenzylideneacetone)dipalladium(0); dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl; lithium tert-butoxide;
In
1,4-dioxane; water;
at 150 ℃;
Microwave irradiation;
DOI:10.1002/anie.201006996
- Guidance literature:
-
Multi-step reaction with 2 steps
1: diethyl ether / 12 h / 20 °C
2: tris-(dibenzylideneacetone)dipalladium(0); 2-dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl; lithium tert-butoxide / 1,4-dioxane; water / 150 °C / Microwave irradiation
With
tris-(dibenzylideneacetone)dipalladium(0); 2-dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl; lithium tert-butoxide;
In
1,4-dioxane; diethyl ether; water;
DOI:10.1002/anie.201006996
- Guidance literature:
-
Multi-step reaction with 3 steps
1: rac-Pro-OH / water; dimethyl sulfoxide / 2.5 h / 46 °C / Microwave irradiation
2: diethyl ether / 12 h / 20 °C
3: tris-(dibenzylideneacetone)dipalladium(0); dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl; lithium tert-butoxide / 1,4-dioxane; water / 150 °C / Microwave irradiation
With
tris-(dibenzylideneacetone)dipalladium(0); dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl; rac-Pro-OH; lithium tert-butoxide;
In
1,4-dioxane; diethyl ether; water; dimethyl sulfoxide;
1: Mannich reaction;
DOI:10.1002/anie.201006996
