(2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid

Base Information

Chemical Name:(2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid
CAS No.:89886-73-7
Molecular Formula:C₆H₈O₅
Molecular Weight:160.127
Hs Code.:2918990090
European Community (EC) Number:694-469-4
DSSTox Substance ID:DTXSID90452478
Nikkaji Number:J1.187.542D
Wikidata:Q76416490
Mol file:89886-73-7.mol

Synonyms:89886-73-7;(2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid;(2S,3S)-3-ethoxycarbonyloxirane-2-carboxylic Acid;(2S,3S)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester;(2S,3S)-3-(Ethoxycarbonyl)-oxirane-2-carboxylic acid;SCHEMBL1806931;DTXSID90452478;MWMZDXCRDIBPCO-IMJSIDKUSA-N;84518-79-6;AKOS016000392;CS-0169238;(2S,3S)-epoxybutanedioic acid monoethyl ester;(2S,3S)-3-ethoxycarbonyloxirane-2-carboxlic acid;A853588;(2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylicacid;(2S, 3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid;2,3-oxiranedicarboxylic acid,monoethyl ester,(2s,3s)-;2,3-Oxiranedicarboxylicacid,monoethylester,(2S,3S)-(9CI);(2S,3S)-3-(Ethoxycarbonyl)oxirane-2-carboxylic acid, 95%

Suppliers and Price of (2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2S,3S)-2,3-OxiranedicarboxylicAcidMonoethylEster
100mg
$ 1060.00

TRC
(2S,3S)-2,3-OxiranedicarboxylicAcidMonoethylEster
10mg
$ 135.00

American Custom Chemicals Corporation
(2S,3S)-3-(ETHOXYCARBONYL)OXIRANE-2-CARBOXYLIC ACID 95.00%
5G
$ 3405.15

American Custom Chemicals Corporation
(2S,3S)-3-(ETHOXYCARBONYL)OXIRANE-2-CARBOXYLIC ACID 95.00%
5MG
$ 495.80

ACHEMBLOCK
(2S,3S)-3-(Ethoxycarbonyl)oxirane-2-carboxylicacid 95%
250MG
$ 375.00

ACHEMBLOCK
(2S,3S)-3-(Ethoxycarbonyl)oxirane-2-carboxylicacid 95%
100MG
$ 235.00

Total 16 raw suppliers

Chemical Property of (2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid

Chemical Property:

Boiling Point:278.9±40.0 oC (760 Torr)
PKA:3.14±0.40(Predicted)
Flash Point:118.5±20.8 oC
PSA：76.13000
Density:1.447±0.06 g/cm3 (20 oC 760 Torr)
LogP:-0.59850
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:-0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:160.03717335
Heavy Atom Count:11
Complexity:187

Purity/Quality:

97% ^*data from raw suppliers

(2S,3S)-2,3-OxiranedicarboxylicAcidMonoethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1C(O1)C(=O)O
Isomeric SMILES:CCOC(=O)[C@@H]1[C@H](O1)C(=O)O
Uses (2S,3S)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester is used in the synthesis of aza-peptidyl inhibitors of lysosomal asparaginyl endopeptidase, legumain. Also used in the synthesis of irreversible epidermal growth factor receptor inhibitors and probes for cathespins.

Technology Process of (2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid

There total 7 articles about (2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%