C₁₇H₂₄O₆S

Base Information

• Chemical Name: C₁₇H₂₄O₆S
• CAS No.: 1611459-89-2
• Molecular Formula: C₁₇H₂₄O₆S
• Molecular Weight: 356.44
• Mol file: 1611459-89-2.mol

Synonyms:C₁₇H₂₄O₆S

Chemical Property of C₁₇H₂₄O₆S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₂₄O₆S

There total 9 articles about C₁₇H₂₄O₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3-[(4'R,5'R)-5'-(benzyloxy)-2',2'-dimethyl-1',3'-dioxan-4'-yl]prop-2-en-1-ol (1611459-86-9) + methanesulfonyl chloride (124-63-0) → C17H24O6S (1611459-89-2)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 0.666667h; Inert atmosphere;

DOI:10.1016/j.tetasy.2014.04.002

Reference yield:

C18H18O5 (1611459-82-5) → C17H24O6S (1611459-89-2)

Guidance literature:

Multi-step reaction with 7 steps

1.1: sodium tetrahydroborate / methanol; dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

2.1: toluene-4-sulfonic acid / dichloromethane / 2 h / 20 °C / Inert atmosphere

3.1: potassium carbonate; methanol / 4.42 h / 0 - 20 °C / Inert atmosphere

4.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / acetonitrile / 1 h / Inert atmosphere; Reflux

5.1: sodium hydride / mineral oil; tetrahydrofuran / 0.42 h / -10 - 0 °C / Inert atmosphere

5.2: 1.5 h / 0 °C / Inert atmosphere

6.1: diisobutylaluminium hydride / dichloromethane; toluene / 0.5 h / -50 - -30 °C / Inert atmosphere

7.1: triethylamine / dichloromethane / 0.67 h / 0 - 20 °C / Inert atmosphere

With methanol; sodium tetrahydroborate; sodium hydride; diisobutylaluminium hydride; potassium carbonate; toluene-4-sulfonic acid; triethylamine; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; methanol; dichloromethane; toluene; acetonitrile; mineral oil; 5.1: |Horner-Wadsworth-Emmons Olefination;

DOI:10.1016/j.tetasy.2014.04.002

Reference yield:

1,2-O-isopropylidene-3-O-benzyl-5-O-triphenylmethyl-α-D-xylofuranoside (185541-37-1) → C17H24O6S (1611459-89-2)

Guidance literature:

Multi-step reaction with 11 steps

1.1: toluene-4-sulfonic acid / methanol; dichloromethane / 1 h / 20 °C / Inert atmosphere

2.1: dmap; pyridine / 1.67 h / 0 - 20 °C / Inert atmosphere

3.1: trifluoroacetic acid / water / 6 h / 0 °C / Inert atmosphere

4.1: sodium periodate / methanol; water / 1 h / 20 °C / Inert atmosphere

5.1: sodium tetrahydroborate / methanol; dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

6.1: toluene-4-sulfonic acid / dichloromethane / 2 h / 20 °C / Inert atmosphere

7.1: potassium carbonate; methanol / 4.42 h / 0 - 20 °C / Inert atmosphere

8.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / acetonitrile / 1 h / Inert atmosphere; Reflux

9.1: sodium hydride / mineral oil; tetrahydrofuran / 0.42 h / -10 - 0 °C / Inert atmosphere

9.2: 1.5 h / 0 °C / Inert atmosphere

10.1: diisobutylaluminium hydride / dichloromethane; toluene / 0.5 h / -50 - -30 °C / Inert atmosphere

11.1: triethylamine / dichloromethane / 0.67 h / 0 - 20 °C / Inert atmosphere

With pyridine; methanol; dmap; sodium tetrahydroborate; sodium periodate; sodium hydride; diisobutylaluminium hydride; potassium carbonate; toluene-4-sulfonic acid; triethylamine; trifluoroacetic acid; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; methanol; dichloromethane; water; toluene; acetonitrile; mineral oil; 9.1: |Horner-Wadsworth-Emmons Olefination;

DOI:10.1016/j.tetasy.2014.04.002

upstream raw materials:

C₁₈H₁₈O₅

1,2-O-isopropylidene-3-O-benzyl-5-O-triphenylmethyl-α-D-xylofuranoside

5-O-benzoyl-3-O-benzyl-1,2-O-isopropylidene-α-D-xylofuranose

(2R,3R)-3-(benzyloxy)-2,4-dihydroxybutyl benzoate

Downstream raw materials:

(4R)-4-[(1'R,2'R)-2'-(benzyloxy)-1',3'-dihydroxypropyl]oxazolidin-2-one

(4R)-4-[(1'R,2'R)-2'-(benzyloxy)-1'-hydroxy-3'-(trityloxy)propyl]oxazolidin-2-one

(4R)-3-benzyl-4-[(1'R,2'R)-1',2'-bis(benzyloxy)-3'-(trityloxy)propyl]oxazolidin-2-one

(4R)-3-benzyl-4-[(1'R,2'R)-1',2'-bis(benzyloxy)-3'-hydroxypropyl]oxazolidin-2-one