ethyl pyrido[2,1-α]isoindole-6-carboxylate

Base Information

• Chemical Name: ethyl pyrido[2,1-α]isoindole-6-carboxylate
• CAS No.: 1111165-53-7
• Molecular Formula: C₁₅H₁₃NO₂
• Molecular Weight: 239.274
• Mol file: 1111165-53-7.mol

Synonyms:ethyl pyrido[2,1-α]isoindole-6-carboxylate

Chemical Property of ethyl pyrido[2,1-α]isoindole-6-carboxylate

Chemical Property:

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Technology Process of ethyl pyrido[2,1-α]isoindole-6-carboxylate

There total 1 articles about ethyl pyrido[2,1-α]isoindole-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

2-phenylpyridine (1008-89-5) + glyoxylic acid ethyl ester (924-44-7) → ethyl pyrido[2,1-α]isoindole-6-carboxylate (1111165-53-7) + ethyl 2-hydroxy-2-(2-(pyridin-2-yl)phenyl)acetate (1312617-85-8)

Guidance literature:

With silver hexafluoroantimonate; carbonyl(pentamethylcyclopentadienyl)cobalt diiodide; copper diacetate; In 1,2-dichloro-ethane; at 60 ℃; for 24h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.6b02421

upstream raw materials:

2-phenylpyridine

glyoxylic acid ethyl ester