2-(Cyanomethyl)benzene-1-sulfonyl chloride

Base Information

Chemical Name:2-(Cyanomethyl)benzene-1-sulfonyl chloride
CAS No.:27350-00-1
Molecular Formula:C₈H₆ClNO₂S
Molecular Weight:215.66
Hs Code.:
European Community (EC) Number:893-003-9

Synonyms:2-(cyanomethyl)benzene-1-sulfonyl chloride;27350-00-1;2-(cyanomethyl)benzenesulfonyl chloride;SCHEMBL7076152;CBA35000;AKOS006333330;2-(cyanomethyl)benzene-1-sulfonylchloride;EN300-191385

Suppliers and Price of 2-(Cyanomethyl)benzene-1-sulfonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(Cyanomethyl)benzene-1-sulfonyl chloride

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:214.9807773
Heavy Atom Count:13
Complexity:311

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CC#N)S(=O)(=O)Cl

Technology Process of 2-(Cyanomethyl)benzene-1-sulfonyl chloride

There total 1 articles about 2-(Cyanomethyl)benzene-1-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 27350-00-1
2-cyanomethyl-benzenesulfonyl chloride

Guidance literature:: o-Amino-phenylacetonitril, 1) Diazotieren, 2) Sulfochlorierung;
DOI:10.1002/cber.19701030638

Reference yield:

: 27350-00-1
2-cyanomethyl-benzenesulfonyl chloride

: 27350-01-2
2-cyanomethyl-benzenesulfonamide

Guidance literature:: With ammonium hydroxide; In acetonitrile; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1016/j.bmcl.2014.02.054

Reference yield:

: 27350-00-1
2-cyanomethyl-benzenesulfonyl chloride

: 1602577-69-4
N-(2-(cyanomethyl)phenylsulfonyl)-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium hydroxide / acetonitrile / 1 h / 0 - 20 °C / Inert atmosphere

2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / N,N-dimethyl-formamide / 4 h / 20 °C / Inert atmosphere

With dmap; ammonium hydroxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.bmcl.2014.02.054