3-(p-aminophenyl)propyl p-tolyl sulphide

Base Information

• Chemical Name: 3-(p-aminophenyl)propyl p-tolyl sulphide
• CAS No.: 99676-64-9
• Molecular Formula: C₁₆H₁₉NS
• Molecular Weight: 257.4
• Mol file: 99676-64-9.mol

Synonyms:3-(p-aminophenyl)propyl p-tolyl sulphide

Chemical Property of 3-(p-aminophenyl)propyl p-tolyl sulphide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(p-aminophenyl)propyl p-tolyl sulphide

There total 4 articles about 3-(p-aminophenyl)propyl p-tolyl sulphide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3-(p-nitrophenyl)propyl p-tolyl sulphide (99676-63-8) → 3-(p-aminophenyl)propyl p-tolyl sulphide (99676-64-9)

Guidance literature:

With iron; acetic acid; In water; acetone; for 1.5h; Heating;

Reference yield:

3-Phenyl-1-propanol (122-97-4) → 3-(p-aminophenyl)propyl p-tolyl sulphide (99676-64-9)

Guidance literature:

Multi-step reaction with 4 steps

1: Et₃N / CH₂Cl₂ / 0.25 h

2: 50 percent / HNO₃ / 5 h / Ambient temperature

3: 99 percent / NaOMe / methanol

4: 93 percent / Fe, AcOH / acetone; H₂O / 1.5 h / Heating

With nitric acid; sodium methylate; iron; acetic acid; triethylamine; In methanol; dichloromethane; water; acetone;

Reference yield:

3-phenylpropanol methanesulfonate (69804-99-5) → 3-(p-aminophenyl)propyl p-tolyl sulphide (99676-64-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 50 percent / HNO₃ / 5 h / Ambient temperature

2: 99 percent / NaOMe / methanol

3: 93 percent / Fe, AcOH / acetone; H₂O / 1.5 h / Heating

With nitric acid; sodium methylate; iron; acetic acid; In methanol; water; acetone;

upstream raw materials:

3-(p-nitrophenyl)propyl p-tolyl sulphide

3-Phenyl-1-propanol

3-phenylpropanol methanesulfonate

3-(4'-nitrophenyl)propyl methanesulfonate

Downstream raw materials:

1-(5-fluorouracil-1-yl)-3-(p-phthalimidophenyl)propyl p-tolyl sulphide

2-{4-[3-(5-Fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-(2-hydroxy-ethoxy)-propyl]-phenyl}-isoindole-1,3-dione

2-{4-[3-(5-Fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-isopropoxy-propyl]-phenyl}-isoindole-1,3-dione

N-phenyl>phthalimide

Refernces