N⁽¹⁾-(2-((7-acetamidonaphthalen-2-yl)amino)-2-oxoethyl)-N⁽³⁾-(2-ethylhexyl)-4,6-bis((2-ethylhexyl)oxy)isophthalamide

Base Information

• Chemical Name: N⁽¹⁾-(2-((7-acetamidonaphthalen-2-yl)amino)-2-oxoethyl)-N⁽³⁾-(2-ethylhexyl)-4,6-bis((2-ethylhexyl)oxy)isophthalamide
• CAS No.: 1260632-47-0
• Molecular Formula: C₄₆H₆₈N₄O₆
• Molecular Weight: 773.069

Synonyms:N⁽¹⁾-(2-((7-acetamidonaphthalen-2-yl)amino)-2-oxoethyl)-N⁽³⁾-(2-ethylhexyl)-4,6-bis((2-ethylhexyl)oxy)isophthalamide

Chemical Property of N⁽¹⁾-(2-((7-acetamidonaphthalen-2-yl)amino)-2-oxoethyl)-N⁽³⁾-(2-ethylhexyl)-4,6-bis((2-ethylhexyl)oxy)isophthalamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N⁽¹⁾-(2-((7-acetamidonaphthalen-2-yl)amino)-2-oxoethyl)-N⁽³⁾-(2-ethylhexyl)-4,6-bis((2-ethylhexyl)oxy)isophthalamide

There total 5 articles about N⁽¹⁾-(2-((7-acetamidonaphthalen-2-yl)amino)-2-oxoethyl)-N⁽³⁾-(2-ethylhexyl)-4,6-bis((2-ethylhexyl)oxy)isophthalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

N-(7-aminonaphthalen-2-yl)acetamide (1260632-40-3) + 2-(5-((2-ethylhexyl)carbamoyl)-2,4-bis((2-ethylhexyl)oxy)benzamido)acetic acid (1260632-44-7) → N(1)-(2-((7-acetamidonaphthalen-2-yl)amino)-2-oxoethyl)-N(3)-(2-ethylhexyl)-4,6-bis((2-ethylhexyl)oxy)isophthalamide (1260632-47-0)

Guidance literature:

2-(5-((2-ethylhexyl)carbamoyl)-2,4-bis((2-ethylhexyl)oxy)benzamido)acetic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 2h; Inert atmosphere;

N-(7-aminonaphthalen-2-yl)acetamide; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ol102522m

Reference yield:

C36H62N2O6 → N(1)-(2-((7-acetamidonaphthalen-2-yl)amino)-2-oxoethyl)-N(3)-(2-ethylhexyl)-4,6-bis((2-ethylhexyl)oxy)isophthalamide (1260632-47-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: water; sodium hydroxide / methanol / 6 h

2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 2 h / Inert atmosphere

2.2: 24 h / 20 °C / Inert atmosphere

With water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; In methanol; dichloromethane;

DOI:10.1021/ol102522m

Reference yield:

2,7-Dihydroxynaphthalene (582-17-2) → N(1)-(2-((7-acetamidonaphthalen-2-yl)amino)-2-oxoethyl)-N(3)-(2-ethylhexyl)-4,6-bis((2-ethylhexyl)oxy)isophthalamide (1260632-47-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: ammonium hydroxide; sodium hydrogensulfite / 7 h / 170 °C

2.1: triethylamine / dichloromethane / 0.33 h / 20 °C

3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 2 h / Inert atmosphere

3.2: 24 h / 20 °C / Inert atmosphere

With benzotriazol-1-ol; ammonium hydroxide; sodium hydrogensulfite; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; 1.1: Bucherer synthesis;

DOI:10.1021/ol102522m

upstream raw materials:

N-(7-aminonaphthalen-2-yl)acetamide

2-(5-((2-ethylhexyl)carbamoyl)-2,4-bis((2-ethylhexyl)oxy)benzamido)acetic acid

5-((2-ethylhexyl)carbamoyl)-2,4-bis((2-ethylhexyl)oxy)benzoic acid

2,7-Dihydroxynaphthalene

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1260632-47-0 N⁽¹⁾-(2-((7-acetamidonaphthalen-2-yl)amino)-2-oxoethyl)-N⁽³⁾-(2-ethylhexyl)-4,6-bis((2-ethylhexyl)oxy)isophthalamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send