Technology Process of 4-(2-heptyl-2H-tetrazol-5-yl)phenol
There total 4 articles about 4-(2-heptyl-2H-tetrazol-5-yl)phenol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
4-(2-heptyl-2H-tetrazol-5-yl)phenyl acetate;
With
potassium hydroxide;
In
methanol; water;
for 12h;
Reflux;
With
hydrogenchloride;
In
water;
pH=2;
Cooling with ice;
DOI:10.1039/c3tc30966e
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium azide; ammonium chloride / N,N-dimethyl-formamide / 24 h / 120 °C
2.1: sodium hydroxide / water / 0.5 h / Cooling with ice
3.1: potassium carbonate / acetone / 48 h / Reflux
4.1: potassium hydroxide / water; methanol / 12 h / Reflux
4.2: pH 2 / Cooling with ice
With
sodium azide; potassium carbonate; ammonium chloride; potassium hydroxide; sodium hydroxide;
In
methanol; water; N,N-dimethyl-formamide; acetone;
DOI:10.1039/c3tc30966e
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydroxide / water / 0.5 h / Cooling with ice
2.1: potassium carbonate / acetone / 48 h / Reflux
3.1: potassium hydroxide / water; methanol / 12 h / Reflux
3.2: pH 2 / Cooling with ice
With
potassium carbonate; potassium hydroxide; sodium hydroxide;
In
methanol; water; acetone;
DOI:10.1039/c3tc30966e
