Technology Process of C10H11IO2
There total 3 articles about C10H11IO2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-phenylbut-2-yne-1,4-diol;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran; diethyl ether;
at 0 - 25 ℃;
for 2h;
Inert atmosphere;
With
ethyl acetate;
In
tetrahydrofuran; diethyl ether;
at 0 ℃;
for 1h;
Inert atmosphere;
With
iodine;
In
tetrahydrofuran; diethyl ether;
at -10 - 0 ℃;
for 1.5h;
regioselective reaction;
Inert atmosphere;
DOI:10.1134/S1070363214030086
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: propyl bromide; magnesium / tetrahydrofuran; diethyl ether / 0.5 h / -10 - -5 °C / Reflux
1.2: -15 - -10 °C
2.1: toluene-4-sulfonic acid; water; methanol / diethyl ether
3.1: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 2 h / 0 - 25 °C / Inert atmosphere
3.2: 1 h / 0 °C / Inert atmosphere
3.3: 1.5 h / -10 - 0 °C / Inert atmosphere
With
methanol; lithium aluminium tetrahydride; water; toluene-4-sulfonic acid; magnesium; propyl bromide;
In
tetrahydrofuran; diethyl ether;
DOI:10.1134/S1070363214030086
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: toluene-4-sulfonic acid; water; methanol / diethyl ether
2.1: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 2 h / 0 - 25 °C / Inert atmosphere
2.2: 1 h / 0 °C / Inert atmosphere
2.3: 1.5 h / -10 - 0 °C / Inert atmosphere
With
methanol; lithium aluminium tetrahydride; water; toluene-4-sulfonic acid;
In
tetrahydrofuran; diethyl ether;
DOI:10.1134/S1070363214030086
